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R D Bies

Explore the profile of R D Bies including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 527
Followers 0
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Recent Articles
1.
Lemler M, Bies R, Frid M, Sastravaha A, Zisman L, Bohlmeyer T, et al.
Am J Physiol Heart Circ Physiol . 2000 Sep; 279(3):H1365-76. PMID: 10993804
Previous studies have demonstrated that environmentally or genetically induced changes in the intracellular proteins that compose the cytoskeleton can contribute to heart failure. Because neonatal right ventricular myocytes are immature...
2.
Palmer B, Valent S, Holder E, Weinberger H, Bies R
Am J Physiol . 1998 Nov; 275(5):H1707-16. PMID: 9815078
The role of microtubules in modulating cardiomyocyte beta-adrenergic response was investigated in rats with cardiac hypertrophy. Male Sprague-Dawley rats underwent stenosis of the abdominal aorta (hypertensive, HT) or sham operation...
3.
Bies R, Maeda M, Roberds S, Holder E, Bohlmeyer T, Young J, et al.
J Mol Cell Cardiol . 1998 Apr; 29(12):3175-88. PMID: 9441825
5'-mutations in the dystrophin gene can result in cardiomyopathy without clinically-apparent skeletal myopathy. The effect of dystrophin mutations on the assembly and stability of the dystrophin associated protein (DAP) complex...
4.
Morrison D, Bies R, SACKS J
J Am Coll Cardiol . 1997 Feb; 29(2):339-44. PMID: 9014986
Objectives: We sought to compare the short- and long-term mortality rates in patients > or = 70 years old with unstable angina undergoing percutaneous transluminal coronary angioplasty (PTCA) with predicted...
5.
Maeda M, Holder E, Lowes B, Valent S, Bies R
Circulation . 1997 Jan; 95(1):17-20. PMID: 8994410
Background: The cytoskeleton plays an important role in maintaining cell structure and integrity. Defects in cytoskeletal proteins can cripple cell strength and may cause cardiomyopathy. We analyzed heart tissues from...
6.
Crowley S, Bies R, Morrison D
Cathet Cardiovasc Diagn . 1996 Jul; 38(3):256-62. PMID: 8804783
Angioplasty of the internal mammary artery (IMA) bypass graft has been shown to be a safe and effective revascularization procedure. However, angiographic and long term clinical outcomes in the high-risk...
7.
Torre-Amione G, Kapadia S, Lee J, Durand J, Bies R, Young J, et al.
Circulation . 1996 Feb; 93(4):704-11. PMID: 8640999
Background: Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine that produces negative inotropic effects in the heart. Recently, elevated levels of TNF-alpha have been reported in patients with advanced congestive...
8.
Holder E, Maeda M, Bies R
Hum Genet . 1996 Feb; 97(2):232-9. PMID: 8566960
Dystrophin mRNA transcripts from the P (Purkinje) promoter were shown to be differentially expressed in human skeletal muscle, heart, and brain. The expression pattern was characteristic of tissue type and...
9.
Torre-Amione G, Kapadia S, Lee J, Bies R, Lebovitz R, Mann D
Circulation . 1995 Sep; 92(6):1487-93. PMID: 7664431
Background: Tumor necrosis factor-alpha (TNF-alpha), a proinflammatory cytokine with potent negative inotropic properties, is elaborated in septic shock, acute myocarditis, reperfusion injury, and congestive heart failure. TNF-alpha acts by binding...
10.
Maeda M, Taft C, Bush E, Holder E, Bailey W, Neville H, et al.
J Biol Chem . 1995 Sep; 270(35):20246-9. PMID: 7657592
The protein product of the myotonic dystrophy (DM) gene is a putative serine-threonine protein kinase (DM kinase). Previous reports have characterized the DM gene product as various 50-62-kDa proteins. The...