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R Carpenedo

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Articles 20
Citations 344
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Recent Articles
1.
Brauneis S, Araimo F, Rossi M, Russo D, Mammucari M, Maggiori E, et al.
Clin Ter . 2023 Jun; 174(4):336-342. PMID: 37378503
Background: Mesotherapy is a technique through which active ingredients are administered into the thickness of the skin in order to increase the local analgesic effect. Methods: 141 patients with spinal...
2.
Natoli S, Carpenedo R, Chine E, Vannicola F, Leonardis F, Dauri M
Eur Rev Med Pharmacol Sci . 2021 Aug; 25(14):4854-4867. PMID: 34337735
Objective: The purpose of this narrative review is to discuss the available information regarding the currently utilized COVID-19 therapies (and the evidence level supporting them) and opioids for chronic pain...
3.
Dauri M, Faria S, Gatti A, Celidonio L, Carpenedo R, Sabato A
Curr Drug Targets . 2009 Aug; 10(8):716-33. PMID: 19702520
Background: Gabapentin and pregabalin inhibit Ca(2+) currents via high-voltage-activated channels containing the alpha2delta-1 subunit, reducing neurotransmitter release and attenuating the postsynaptic excitability. They are antiepileptic drugs successfully used also for...
4.
Carpenedo R, Pittaluga A, Cozzi A, Attucci S, Galli A, Raiteri M, et al.
Eur J Neurosci . 2001 Jun; 13(11):2141-7. PMID: 11422455
Kynurenic acid is a tryptophan metabolite provided with antagonist activity on ionotropic glutamate and alpha7 nicotinic acetylcholine receptors. We noticed that in rats with a dialysis probe placed in the...
5.
Moroni F, Cozzi A, Peruginelli F, Carpenedo R, Pellegrini-Giampietro D
Adv Exp Med Biol . 2000 Mar; 467:199-206. PMID: 10721057
The neuroprotective effects of two kynurenine hydroxylase inhibitors, (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfona mide (Ro 61-8048), were studied in vitro and in vivo. In organotypic hippocampal slice cultures deprived of oxygen...
6.
Mannaioni G, Carpenedo R, Corradetti R, Carla V, Venturini I, Baraldi M, et al.
Adv Exp Med Biol . 2000 Mar; 467:155-67. PMID: 10721052
Oxindole administration (1-100 mg/kg i.p.) to mammals decreases locomotor activity, reduces muscular tone and blood pressure and at larger doses causes coma and death. Utilizing both HPLC and GC/MS, we...
7.
Bergqvist P, Carpenedo R, APELQVIST G, Moroni F, Bengtsson F
Pharmacol Toxicol . 1999 Oct; 85(3):138-43. PMID: 10522754
It has previously been shown that the neurodepressant L-tryptophan metabolite oxindole is increased in the blood and brain of rats with fulminant hepatic failure and in the blood of cirrhotic...
8.
Cozzi A, Carpenedo R, Moroni F
J Cereb Blood Flow Metab . 1999 Jul; 19(7):771-7. PMID: 10413032
Two kynurenine hydroxylase inhibitors, (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfona mide (Ro 61-8048), have been tested as neuroprotective agents on brain lesions induced by bilateral carotid occlusion in gerbils or by middle...
9.
Mannaioni G, Carpenedo R, Pugliese A, Corradetti R, Moroni F
Br J Pharmacol . 1999 Jan; 125(8):1751-60. PMID: 9886767
1. The aim of the present work was to investigate the electrophysiological effects of oxindole, a tryptophan metabolite present in rat blood and brain, and recently proposed as a contributing...
10.
Furlanetto S, Tognini C, Carpenedo R, La Porta E, Pinzauti S
J Pharm Biomed Anal . 1998 Dec; 18(1-2):67-73. PMID: 9863944
Validation of an adsorptive stripping voltammetric method for kynurenic acid determination in urine, was presented. The selection of appropriate validation parameters, the design consideration for evaluation and the problem of...