R C Pedersen
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Explore the profile of R C Pedersen including associated specialties, affiliations and a list of published articles.
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30
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200
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Recent Articles
11.
Li X, Warren D, Gregoire J, Pedersen R, Lee A
Mol Endocrinol
. 1989 Dec;
3(12):1944-52.
PMID: 2628731
Based on the striking sequence identity between the amino acid sequence of rat steroidogenesis-activator polypeptide (SAP) and the carboxyl terminus of the 78,000 dalton glucose-regulated protein (GRP78), the precursor-product relationship...
12.
Mertz L, Pedersen R
J Biol Chem
. 1989 Sep;
264(26):15274-9.
PMID: 2549056
The behavior of steroidogenesis activator polypeptide (SAP), a recently described modulator of cholesterol side-chain cleavage activity (Pedersen, R. C., and Brownie, A. C. (1987) Science 236, 188-190), was investigated in...
13.
Frustaci J, Mertz L, Pedersen R
Mol Cell Endocrinol
. 1989 Jul;
64(2):137-43.
PMID: 2551755
Steroidogenesis activator polypeptide (SAP), a cytosolic stimulator of cholesterol side-chain cleavage (cholesterol SCC) previously characterized in the rat, was isolated from guinea pig adrenal cortex. This factor exhibited behavior on...
14.
Mertz L, Pedersen R
Endocr Res
. 1989 Jan;
15(1-2):101-15.
PMID: 2759046
Cholesterol side-chain cleavage is sensitive to antibiotic inhibitors of protein synthesis, suggesting that a labile protein may play a regulatory role in this process. We have previously characterized such a...
15.
Pedersen R, BROWNIE A
Science
. 1987 Apr;
236(4798):188-90.
PMID: 3563495
A cycloheximide-sensitive protein responsive to adenosine 3',5'-monophosphate has been postulated to participate in the regulation of cholesterol side-chain cleavage activity in steroidogenic tissues. Such a steroidogenesis activator polypeptide (SAP) had...
16.
Pedersen R, BROWNIE A
Mol Cell Endocrinol
. 1987 Mar;
50(1-2):149-56.
PMID: 3582725
Gamma 3-melanotropin (gamma 3-MSH) facilitates a rapid, dose-dependent, and cycloheximide-insensitive increase in the concentration of mitochondrial free cholesterol in the adrenals of hypophysectomized rats. Physiological concentrations of various synthetic and...
17.
High density lipoprotein influences the response of rat adrenocortical cells to gamma 3-melanotropin
Pedersen R, BROWNIE A
Mol Cell Endocrinol
. 1987 Mar;
50(1-2):157-64.
PMID: 3034697
Gamma 3-melanotropin (gamma 3-MSH) exhibits a marked dose-dependent synergism with ACTH1-24 on corticosterone production by cells isolated from the inner zones of the rat adrenal cortex. This phenomenon is demonstrated...
18.
Pedersen R
J Steroid Biochem
. 1987 Jan;
27(4-6):731-5.
PMID: 2826905
A steroidogenesis activator polypeptide (SAP) has previously been identified in the rat adrenal cortex (Pedersen and Brownie, Proc. natn. Acad. Sci. U.S.A. 80 (1983) 1882-1886). This factor apparently facilitates the...
19.
BROWNIE A, Pedersen R
J Hypertens Suppl
. 1986 Dec;
4(5):S72-5.
PMID: 3553489
Pro-gamma-melanotropins (pro-gamma-MSH) are implicated in the control of aldosterone secretion by the normal adrenal cortex and in idiopathic hyperaldosteronism. In contrast with other melanotropins (alpha- and beta-MSH), the pro-gamma-MSH increase...
20.
Griffing G, Berelowitz B, Hudson M, Salzman R, Manson J, Aurrechia S, et al.
J Clin Invest
. 1985 Jul;
76(1):163-9.
PMID: 4019776
A non-ACTH aldosterone-stimulating factor(s) has been implicated in the pathogenesis of idiopathic hyperaldosteronism (IHA). Although this factor has not been fully characterized, some evidence suggests that it may be related...