R C Moon
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Explore the profile of R C Moon including associated specialties, affiliations and a list of published articles.
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134
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2184
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Recent Articles
11.
Jang M, Cai L, Udeani G, Slowing K, Thomas C, Beecher C, et al.
Science
. 1997 Jan;
275(5297):218-20.
PMID: 8985016
Resveratrol, a phytoalexin found in grapes and other food products, was purified and shown to have cancer chemopreventive activity in assays representing three major stages of carcinogenesis. Resveratrol was found...
12.
Bacus J, Bacus J, Stoner G, Moon R, Kelloff G, Boone C
J Cell Biochem Suppl
. 1997 Jan;
28-29:21-38.
PMID: 9589347
An assay method that precisely quantitates the cellular and tissue changes associated with early, preinvasive neoplasia is much needed as a surrogate endpoint biomarker (SEB) in clinical trials to predict...
13.
Sgambato A, Han E, Zhang Y, Moon R, Santella R, Weinstein I
Carcinogenesis
. 1995 Sep;
16(9):2193-8.
PMID: 7554074
Dysregulation of cyclin expression has been reported for several human malignancies, including breast cancer. To further investigate the role of cyclin genes in mammary tumorigenesis we analyzed the expression of...
14.
15.
Mehta R, Liu J, Constantinou A, Thomas C, Hawthorne M, You M, et al.
Carcinogenesis
. 1995 Feb;
16(2):399-404.
PMID: 7859373
Brassinin [3-(S-methyldithiocarbamoyl)aminomethyl indole], a phytoalexin first identified as a constituent of cabbage, was synthesized and evaluated for cancer chemopreventive activity. Dose-dependent inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced preneoplastic lesion formation was observed...
16.
Shamon L, Chen C, Mehta R, Steele V, Moon R, Pezzuto J
Anticancer Res
. 1994 Sep;
14(5A):1775-8.
PMID: 7847810
Seventy natural and synthetic compounds were tested for potential to inhibit mutation induced by 7,12-dimethylbenz(a)anthracene (DMBA) in Salmonella typhimurium strain TM677. Results were compared with their ability to inhibit DMBA-induced...
17.
Moon R, Steele V, Kelloff G, Thomas C, Detrisac C, Mehta R, et al.
Anticancer Res
. 1994 May;
14(3A):889-93.
PMID: 8074489
The effects of structurally different antiestrogens, progesterone and the aromatase inhibitor aminoglutethimide, were evaluated for chemopreventive activity in the N-methyl-N-nitrosourea (MNU)-induced mammary carcinogenesis model. Treatment with either RU 16117, progesterone...
18.
Mehta R, Liu J, Constantinou A, Hawthorne M, Pezzuto J, Moon R, et al.
Anticancer Res
. 1994 May;
14(3A):1209-13.
PMID: 8074474
Brassinin, a phytoalexin, is found in Chinese cabbage. Previously, we showed that brassinin significantly inhibited dimethylbenz(a)anthracene (DMBA)-induced mammary lesions in organ culture. Moreover, it was an effective inhibitor against two...
19.
Moon R, Kelloff G, Detrisac C, Steele V, Thomas C, Sigman C
Anticancer Res
. 1994 Jan;
14(1A):5-11.
PMID: 8166455
The chemopreventive efficacy of the schistosomicidal drug oltipraz (5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione) was evaluated against urinary bladder transitional cell carcinoma (TCC) induced in male C57BL/6 x DBA/2FI (BDF) mice by N-butyl-N(4-hydroxybutyl)nitrosamine (OH-BBN). Oltipraz...
20.
Moon R
Adv Exp Med Biol
. 1994 Jan;
364:101-7.
PMID: 7725952
Both epidemiologic and experimental evidence are highly suggestive of an inverse relationship between vitamin A status and cancer induction. However, protection by vitamin A and retinoids has not been a...