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R C Desrosiers

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Articles 213
Citations 10337
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Recent Articles
1.
Bischof G, Shin Y, Fuchs S, Martinez-Navio J, Lauer W, Rakasz E, et al.
Gene Ther . 2017 Jun; 24(8):487-492. PMID: 28660888
The gamma-2 herpesvirus of rhesus monkeys, rhesus monkey rhadinovirus (RRV), persists principally in B cells of its host. We constructed recombinant strains of RRV expressing the rhesus monkey-derived anti-SIV monoclonal...
2.
Renne R, Dittmer D, Kedes D, Schmidt K, Desrosiers R, Luciw P, et al.
J Med Primatol . 2004 Apr; 33(1):1-9. PMID: 15061726
Kaposi's sarcoma-associated herpesvirus (KSHV) is a gamma-herpesvirus associated with Kaposi's sarcoma (KS) and two lymphoproliferative diseases, primary effusion lymphoma (PEL) and multicentric Castleman's disease. Studies on the biology and pathogenesis...
3.
Lifson J, Piatak Jr M, Rossio J, Bess Jr J, Chertova E, Schneider D, et al.
J Med Primatol . 2002 Oct; 31(4-5):205-16. PMID: 12390543
A novel type of whole inactivated simian immunodeficiency virus (SIV) virion vaccine immunogen with functional envelope glycoproteins was evaluated, without adjuvant, in rhesus macaques. Immunogens included purified inactivated virions of...
4.
Murphy W, Page J, SMITH Jr C, Desrosiers R, OBrien S
J Hered . 2002 Apr; 92(6):516-9. PMID: 11948222
The genomes of nonhuman primates have recently become highly visible candidates for full genome analysis, as they provide powerful models of human disease and a better understanding of the evolution...
5.
Evans D, Desrosiers R
Immunol Rev . 2002 Jan; 183:141-58. PMID: 11782254
Individuals infected with human immunodeficiency virus (HIV) and macaques infected with simian immunodeficiency virus (SIV) make vigorous virus-specific antibody and cellular immune responses. Despite these responses, virus replication continues at...
6.
Kaur A, Alexander L, Staprans S, Denekamp L, Hale C, McClure H, et al.
Eur J Immunol . 2001 Dec; 31(11):3207-17. PMID: 11745337
Although CTL escape has been well documented in pathogenic simian immunodeficiency virus (SIV) infection, there is no information on CTL escape in nonpathogenic SIV infection in nonhuman primate hosts like...
7.
Johnson W, Sauvron J, Desrosiers R
J Virol . 2001 Nov; 75(23):11426-36. PMID: 11689624
The transmembrane subunit (TM) of human immunodeficiency virus type 1 (HIV-1) envelope protein contains four well-conserved sites for the attachment of N-linked carbohydrates. To study the contribution of these N-glycans...
8.
Newstein M, Desrosiers R
J Infect Dis . 2001 Oct; 184(10):1262-7. PMID: 11679914
Mutations in human immunodeficiency virus type 1 reverse-transcriptase codons 89 and 184 confer inhibitor resistance and alter the mutation spectrum of the enzyme. Six macaques were inoculated with wild-type or...
9.
Lifson J, Rossio J, Piatak Jr M, Parks T, Li L, Kiser R, et al.
J Virol . 2001 Oct; 75(21):10187-99. PMID: 11581387
Transient antiretroviral treatment with tenofovir, (R)-9-(2-phosphonylmethoxypropyl)adenine, begun shortly after inoculation of rhesus macaques with the highly pathogenic simian immunodeficiency virus (SIV) isolate SIVsmE660, facilitated the development of SIV-specific lymphoproliferative responses...
10.