F Kirchhoff
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Explore the profile of F Kirchhoff including associated specialties, affiliations and a list of published articles.
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Articles
88
Citations
3684
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Recent Articles
1.
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
Jonsson K, Laustsen A, Krapp C, Skipper K, Thavachelvam K, Hotter D, et al.
Nat Commun
. 2017 Feb;
8:14391.
PMID: 28186168
Innate immune activation by macrophages is an essential part of host defence against infection. Cytosolic recognition of microbial DNA in macrophages leads to induction of interferons and cytokines through activation...
2.
Urschitz M, Poets C, Stuck B, Wiater A, Kirchhoff F
HNO
. 2014 Jul;
62(8):582-5.
PMID: 25052895
Background: Adenotonsillar hyperplasia (ATH) can lead to severe breathing disorders, such as impaired nasal breathing, mouth breathing, snoring and obstructive sleep apnea. In such cases ATH should be treated mostly...
3.
Imrich R, Vlcek M, Kerlik J, Vogeser M, Kirchhoff F, Penesova A, et al.
Physiol Res
. 2014 Feb;
63(3):321-9.
PMID: 24564598
The aim of our study was to investigate adrenocortical function in the context of disease activity and inflammatory status in premenopausal RA females. Adrenal glucocorticoid and androgen responses to the...
4.
Catalin B, Cupido A, IancAu M, Albu C, Kirchhoff F
Rom J Morphol Embryol
. 2013 Sep;
54(3):467-72.
PMID: 24068392
Microglia has emerged not only as an essential inflammatory cell but also as a major player in the development of the adult brain. Microglia phagocytize extra-numerical synapses during postnatal development,...
5.
Kirchhoff F, Debarbieux F, Kronland-Martinet C, Cojocaru G, Popa-Wagner A
Rom J Morphol Embryol
. 2012 Nov;
53(3 Suppl):671-5.
PMID: 23188424
Occlusive brain ischemia and micro-strokes are the most frequent brain pathologies, particularly in older patients and a major cause of dementia. Currently, we are missing appropriate methodology to study micro-strokes...
6.
Tchorz J, Tome M, Cloetta D, Sivasankaran B, Grzmil M, Huber R, et al.
Cell Death Dis
. 2012 Jun;
3:e325.
PMID: 22717580
Recent studies identified a highly tumorigenic subpopulation of glioma stem cells (GSCs) within malignant gliomas. GSCs are proposed to originate from transformed neural stem cells (NSCs). Several pathways active in...
7.
Kirchhoff F, Schindler M, Specht A, Arhel N, Munch J
Cell Mol Life Sci
. 2008 Apr;
65(17):2621-36.
PMID: 18438604
More than a decade ago it was established that intact nef genes are critical for efficient viral persistence and greatly accelerate disease progression in SIVmac-infected rhesus macaques and in HIV-1-infected...
8.
Kirchhoff F, Krebs C, Abdulhag U, Meyer-Schwesinger C, Maas R, Helmchen U, et al.
Kidney Int
. 2007 Nov;
73(5):643-50.
PMID: 18033241
The C57BL/6 mouse strain serves as the genetic background of many transgenic and gene knockout models; however, this strain appears to be resistant to hypertension-induced renal injury. We developed a...
9.
Giaume C, Kirchhoff F, Matute C, Reichenbach A, Verkhratsky A
Cell Death Differ
. 2007 Apr;
14(7):1324-35.
PMID: 17431421
Neuroglia represented by astrocytes, oligodendrocytes and microglial cells provide for numerous vital functions. Glial cells shape the micro-architecture of the brain matter; they are involved in information transfer by virtue...
10.
Faure J, Lachenal G, Court M, Hirrlinger J, Chatellard-Causse C, Blot B, et al.
Mol Cell Neurosci
. 2006 Feb;
31(4):642-8.
PMID: 16446100
Accumulating evidence shows that several cell types have the capacity to secrete membrane proteins by incorporating them into exosomes, which are small lipid vesicles derived from the intralumenal membranes of...