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R C Desrosiers

Explore the profile of R C Desrosiers including associated specialties, affiliations and a list of published articles. Areas
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Articles 213
Citations 10337
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Recent Articles
11.
Damania B, Desrosiers R
Philos Trans R Soc Lond B Biol Sci . 2001 Apr; 356(1408):535-43. PMID: 11313010
Gamma-herpesviruses can be found in most primates including Old World an New World monkeys. The gamma-herpesvirinae are grouped into two classes: lymphocryptoviruses (gamma1) and rhadinoviruses (gamma2). The lymphocryptoviruses include Epstein-Barr...
12.
Alexander L, Denekamp L, Czajak S, Desrosiers R
J Virol . 2001 Mar; 75(8):4019-22. PMID: 11264395
We analyzed virus sequences in two monkeys infected with SIVmac239 and two monkeys infected with SHIVnef that maintained high, persisting viral loads. Sequence changes were observed consistently at four loci...
13.
MEANS R, Matthews T, Hoxie J, Malim M, Kodama T, Desrosiers R
J Virol . 2001 Mar; 75(8):3903-15. PMID: 11264379
To better define the effects of sequence variation and tropism on the ability of the simian immunodeficiency virus SIVmac V3 loop to act as a target of antibody-mediated neutralization, a...
14.
Alexander L, Weiskopf E, Greenough T, Gaddis N, Auerbach M, Malim M, et al.
J Virol . 2001 Feb; 74(9):4361-76. PMID: 10756051
Factors accounting for long-term nonprogression may include infection with an attenuated strain of human immunodeficiency virus type 1 (HIV-1), genetic polymorphisms in the host, and virus-specific immune responses. In this...
15.
MEANS R, Desrosiers R
J Virol . 2000 Nov; 74(23):11181-90. PMID: 11070015
Stocks of simian immunodeficiency virus (SIV) from the supernatants of infected cell cultures were used to examine the sensitivity of envelope glycoprotein gp120 to enzymatic deglycosylation and the effects of...
16.
Mori K, Rosenzweig M, Desrosiers R
J Virol . 2000 Oct; 74(22):10852-9. PMID: 11044136
In contrast to the simian immunodeficiency virus SIVmac239, which replicates poorly in rhesus monkey alveolar macrophages, a variant with nine amino acid changes in envelope (SIVmac239/316E) replicates efficiently and to...
17.
Allen T, OConnor D, Jing P, Dzuris J, Mothe B, Vogel T, et al.
Nature . 2000 Oct; 407(6802):386-90. PMID: 11014195
Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections are characterized by early peaks of viraemia that decline as strong cellular immune responses develop. Although it has been shown...
18.
Murphy C, LUCAS W, MEANS R, Czajak S, Hale C, Lifson J, et al.
J Virol . 2000 Aug; 74(17):7745-54. PMID: 10933680
An effective vaccine for AIDS may require development of novel vectors capable of eliciting long-lasting immune responses. Here we report the development and use of replication-competent and replication-defective strains of...
19.
Alexander L, Denekamp L, Knapp A, Auerbach M, Damania B, Desrosiers R
J Virol . 2000 Mar; 74(7):3388-98. PMID: 10708456
The primary sequence of the long unique region L-DNA (L for low GC) of rhesus monkey rhadinovirus (RRV) isolate 26-95 was determined. The L-DNA consists of 130,733 bp that contain...
20.
Damania B, Demaria M, Jung J, Desrosiers R
J Virol . 2000 Feb; 74(6):2721-30. PMID: 10684288
Rhesus monkey rhadinovirus (RRV) is a gamma-2 herpesvirus that exhibits a considerable degree of similarity to the human Kaposi's sarcoma-associated herpesvirus (KSHV). The R1 protein of RRV is distantly related...