R C Austin
Overview
Explore the profile of R C Austin including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
949
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Recent Articles
1.
Ho H, Lhotak S, Solano M, Karimi K, Pincus M, Austin R, et al.
J Dev Orig Health Dis
. 2014 Aug;
4(1):90-7.
PMID: 25080185
Atherosclerosis is the underlying cause of cardiovascular disease and stroke. Endothelial cell dysfunctions are early events in atherosclerosis, resulting in the recruitment of circulating monocytes. The immune system can elicit...
2.
Duivenvoorden W, Beatty L, Lhotak S, Hill B, Mak I, Paulin G, et al.
Br J Cancer
. 2013 Jan;
108(2):327-33.
PMID: 23322200
Background: Evidence suggests that dysregulation of energy-sensing pathways closely associates with renal cell carcinoma (RCC) development. The metabolic regulation is largely controlled by 5'-AMP activated protein kinase (AMPK) which is...
3.
Toltl L, Austin R, Liaw P
J Thromb Haemost
. 2010 Dec;
9(3):582-92.
PMID: 21166994
Background: The endoplasmic reticulum (ER) is responsible for the synthesis and folding of secretory, transmembrane and ER-resident proteins. Conditions that impair protein folding or overwhelm its protein folding capacity disrupt...
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Austin R, Lentz S, Werstuck G
Cell Death Differ
. 2004 Jul;
11 Suppl 1:S56-64.
PMID: 15243582
Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular disease, including ischemic heart disease, stroke, and peripheral vascular disease. Mutations in the enzymes responsible for homocysteine metabolism, particularly cystathionine beta-synthase...
7.
Zhou J, Moller J, Danielsen C, Bentzon J, Ravn H, Austin R, et al.
Arterioscler Thromb Vasc Biol
. 2001 Sep;
21(9):1470-6.
PMID: 11557674
Hyperhomocysteinemia is an independent risk factor for atherothrombosis. However, causality is unproven, and it remains unknown whether hyperhomocysteinemia promotes atherosclerosis, plaque rupture, and/or thrombosis. We evaluated the short- and long-term...
8.
Werstuck G, Lentz S, Dayal S, Hossain G, Sood S, Shi Y, et al.
J Clin Invest
. 2001 May;
107(10):1263-73.
PMID: 11375416
Hepatic steatosis is common in patients having severe hyperhomocysteinemia due to deficiency for cystathionine beta-synthase. However, the mechanism by which homocysteine promotes the development and progression of hepatic steatosis is...
9.
Lohn J, Austin R, Winslet M
J R Soc Med
. 2000 Aug;
93(7):365-8.
PMID: 10928024
No abstract available.
10.
Li P, Wong J, Ayed A, Ngo D, Brade A, Arrowsmith C, et al.
J Biol Chem
. 2000 Apr;
275(26):20127-35.
PMID: 10777512
The p53 tumor suppressor gene and members of the transforming growth factor-beta (TGF-beta) superfamily play central roles in signaling cell cycle arrest and apoptosis (programmed cell death) in normal development...