R B Rogart
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Explore the profile of R B Rogart including associated specialties, affiliations and a list of published articles.
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22
Citations
801
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Recent Articles
1.
Baumgarten C, Dudley Jr S, Rogart R, Fozzard H
Am J Physiol
. 1995 Dec;
269(6 Pt 1):C1356-63.
PMID: 8572163
Unitary conductances of native Na+ channel isoforms (gamma Na) have been determined under a variety of conditions, making comparisons of gamma Na difficult. To allow direct comparison, we measured gamma...
2.
Satin J, Limberis J, KYLE J, Rogart R, Fozzard H
Biophys J
. 1994 Sep;
67(3):1007-14.
PMID: 7811911
The rat brain IIa (BrIIa) Na channel alpha-subunit and the brain beta 1 subunit were coexpressed in Xenopus oocytes, and peak whole-oocyte Na current (INa) was measured at a test...
3.
Doyle D, Guo Y, Lustig S, Satin J, Rogart R, Fozzard H
J Gen Physiol
. 1993 Feb;
101(2):153-82.
PMID: 8384241
Monovalent and divalent cations competitively displace tetrodotoxin and saxitoxin (STX) from their binding sites on nerve and skeletal muscle Na channels. Recent studies of cloned cardiac (toxin-resistant) and brain (toxin-sensitive)...
4.
Satin J, KYLE J, Chen M, Rogart R, Fozzard H
J Membr Biol
. 1992 Oct;
130(1):11-22.
PMID: 1335083
The neonatal rat cardiac Na channel alpha-subunit directed currents in oocytes show characteristic cardiac relative resistance to tetrodotoxin (TTX) block. TTX-sensitive currents obtained by expression in Xenopus oocytes of the...
5.
Satin J, KYLE J, Chen M, Bell P, Cribbs L, Fozzard H, et al.
Science
. 1992 May;
256(5060):1202-5.
PMID: 1375397
The cardiac sodium channel alpha subunit (RHI) is less sensitive to tetrodotoxin (TTX) and saxitoxin (STX) and more sensitive to cadmium than brain and skeletal muscle (microliter) isoforms. An RHI...
6.
Cribbs L, Satin J, Fozzard H, Rogart R
FEBS Lett
. 1990 Nov;
275(1-2):195-200.
PMID: 2175715
We describe the expression of functional Na+ channels in Xenopus oocytes injected with cRNA transcribed from the rat heart I cDNA clone. The expressed rat heart I Na+ currents show...
7.
Kallen R, Sheng Z, Yang J, Chen L, Rogart R, Barchi R
Neuron
. 1990 Feb;
4(2):233-42.
PMID: 2155010
The alpha subunit of a voltage-sensitive sodium channel characteristic of denervated rat skeletal muscle was cloned and characterized. The cDNA encodes a 2018 amino acid protein (SkM2) that is homologous...
8.
Rogart R, Cribbs L, Muglia L, Kephart D, Kaiser M
Proc Natl Acad Sci U S A
. 1989 Oct;
86(20):8170-4.
PMID: 2554302
Voltage-gated Na+ channels in mammalian heart differ from those in nerve and skeletal muscle. One major difference is that tetrodotoxin (TTX)-resistant cardiac Na+ channels are blocked by 1-10 microM TTX,...
9.
Rogart R, deBruyn Kops A, Dzau V
Proc Natl Acad Sci U S A
. 1986 Oct;
83(19):7452-6.
PMID: 2429306
Various Ca-channel blockers differ in cardiovascular action despite common effects at the Ca channel. Many investigators have reported only a single high-affinity receptor for binding of [3H]nitrendipine, a dihydropyridine Ca-channel...
10.