R B Mikkelsen
Overview
Explore the profile of R B Mikkelsen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
55
Citations
757
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lammering G, Hewit T, Hawkins W, Contessa J, Reardon D, Lin P, et al.
J Natl Cancer Inst
. 2001 Jun;
93(12):921-9.
PMID: 11416113
Background: Exposure of human cancer cells to ionizing radiation activates the epidermal growth factor receptor (EGFR), which, in turn, mediates a cytoprotective response that reduces the cells' sensitivity to ionizing...
2.
Leach J, Van Tuyle G, Lin P, Schmidt-Ullrich R, Mikkelsen R
Cancer Res
. 2001 May;
61(10):3894-901.
PMID: 11358802
Transient generation of reactive oxygen or nitrogen (ROS/RNS), detected with dihydrodichlorofluoroscein by fluorescence microscopy, occurs within minutes of exposing cells to ionizing radiation. In the 1-10 Gy dose range, the...
3.
Bowers G, Reardon D, Hewitt T, Dent P, Mikkelsen R, Valerie K, et al.
Oncogene
. 2001 Apr;
20(11):1388-97.
PMID: 11313882
Activation of the epidermal growth receptor (ErbB1) occurs within minutes of a radiation exposure. Immediate downstream consequences of this activation are currently indistinguishable from those obtained with growth factors (GF),...
4.
Lammering G, Valerie K, Lin P, Mikkelsen R, Contessa J, Feden J, et al.
Clin Cancer Res
. 2001 Apr;
7(3):682-90.
PMID: 11297265
The epidermal growth factor receptor (EGFR) plays an important role in neoplastic growth control of malignant gliomas. We have demonstrated that radiation activates EGFR Tyr-phosphorylation (EGFR Tyr-P) and the proliferation...
5.
Schmidt-Ullrich R, Dent P, Grant S, Mikkelsen R, Valerie K
Radiat Res
. 2000 Feb;
153(3):245-57.
PMID: 10669545
Exposure of cells to ionizing radiation results in complex cellular responses resulting in cell death and altered proliferation states. The underlying cytotoxic, cytoprotective and cellular stress responses to radiation are...
6.
Schmidt-Ullrich R, Contessa J, Dent P, Mikkelsen R, Valerie K, Reardon D, et al.
Radiat Oncol Investig
. 2000 Jan;
7(6):321-30.
PMID: 10644055
No abstract available.
7.
Todd D, Mikkelsen R, Rorrer W, Valerie K, Schmidt-Ullrich R
J Recept Signal Transduct Res
. 1999 Oct;
19(6):885-908.
PMID: 10533979
Previous studies demonstrated that ionizing radiation activates the epidermal growth factor receptor (EGFR), as measured by Tyr autophosphorylation, and induces transient increases in cytosolic free [Ca2+], [Ca2+]f. The mechanistic linkage...
8.
Tombes R, Mikkelsen R, Jarvis W, Grant S
Biochim Biophys Acta
. 1999 Oct;
1452(1):1-11.
PMID: 10525155
Over two dozen alternative splice variants of CaMK-II, the type II Ca(2+)/CaM-dependent protein kinase, are encoded from four genes (alpha, beta, gamma and delta) in mammalian cells. Isozymes of alpha...
9.
Reardon D, Contessa J, Mikkelsen R, Valerie K, Amir C, Dent P, et al.
Oncogene
. 1999 Sep;
18(33):4756-66.
PMID: 10467423
Exposure of MDA-MB-231 human mammary carcinoma cells to an ionizing radiation dose of 2 Gy results in immediate activation and Tyr phosphorylation of the epidermal growth factor receptor (EGFR). Doxycycline...
10.
Contessa J, Reardon D, Todd D, Dent P, Mikkelsen R, Valerie K, et al.
Clin Cancer Res
. 1999 Feb;
5(2):405-11.
PMID: 10037190
Ionizing radiation activates the epidermal growth factor receptor (EGFR) and downstream signaling involving the cytoprotective mitogen-activated protein kinase (MAPK) pathway. In our effort to investigate the role of EGFR in...