R A Voskuyl
Overview
Explore the profile of R A Voskuyl including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
38
Citations
322
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Leaf A, Kang J, Xiao Y, Billman G, Voskuyl R
J Membr Biol
. 1999 Nov;
172(1):1-11.
PMID: 10552009
It has been shown in animals and probably in humans, that n-3 polyunsaturated fatty acids (PUFAs) are antiarrhythmic. We report recent studies on the antiarrhythmic actions of PUFAs. The PUFAs...
12.
Leaf A, Kang J, Xiao Y, Billman G, Voskuyl R
Prostaglandins Leukot Essent Fatty Acids
. 1999 Sep;
60(5-6):307-12.
PMID: 10471113
It has been shown in animals and probably in humans, that n-3 polyunsaturated fatty acids (PUFAs) are antiarrhythmic. The free PUFAs stabilize the electrical activity of isolated cardiac myocytes by...
13.
Cleton A, Mazee D, Voskuyl R, Danhof M
Br J Pharmacol
. 1999 Jun;
127(1):227-35.
PMID: 10369477
The objective of this investigation was to characterize quantitatively the influence of the rate of increase in blood concentrations on the pharmacodynamics of midazolam in rats. The pharmacodynamics of midazolam...
14.
Della Paschoa O, Voskuyl R, Danhof M
Br J Pharmacol
. 1999 Jan;
125(7):1610-6.
PMID: 9884091
Treatment of epilepsy with a combination of antiepileptic drugs remains the therapeutic choice when monotherapy fails. In this study, we apply pharmacokinetic-pharmacodynamic modelling to characterize the interaction between phenytoin (PHT)...
15.
Della Paschoa O, Kruk M, HAMSTRA R, Voskuyl R, Danhof M
Br J Pharmacol
. 1998 Dec;
125(5):997-1004.
PMID: 9846637
1. In this study we used cortical stimulation to assess the effects of phenytoin (PHT), sodium valproate (VPA), and their interaction on total motor seizure and on the constituent elements...
16.
Della Paschoa O, Kruk M, Voskuyl R, Danhof M
Brain Res
. 1998 Dec;
814(1-2):199-208.
PMID: 9838114
Individual variability and numerous interactions between pharmacokinetics, pharmacodynamics, and homeostatic factors complicate the study of the anticonvulsant effect in animal models of seizure activity. In theory, both individual variability and...
17.
Cleton A, Voskuyl R, Danhof M
Br J Pharmacol
. 1998 Dec;
125(4):615-20.
PMID: 9831893
1. The objective of this investigation was to determine quantitatively whether experimental epilepsy is associated with a change in the pharmacodynamics of benzodiazepines in vivo. For that purpose the pharmacodynamics...
18.
Voskuyl R, Vreugdenhil M, Kang J, Leaf A
Eur J Pharmacol
. 1998 May;
341(2-3):145-52.
PMID: 9543232
Recent studies have shown that long-chain polyunsaturated fatty acids can prevent cardiac arrhythmias, attributed to the reduction in excitability of cardiomyocytes, owing mainly to a shift in hyperpolarizing direction of...
19.
Della Paschoa O, Mandema J, Voskuyl R, Danhof M
J Pharmacol Exp Ther
. 1998 Mar;
284(2):460-6.
PMID: 9454785
In this study a pharmacokinetic-pharmacodynamic model is proposed for drugs with nonlinear elimination kinetics. We applied such an integrated approach to characterize the pharmacokinetic-pharmacodynamic relationship of phenytoin. In parallel, the...
20.
Della Paschoa O, Kruk M, HAMSTRA R, Voskuyl R, Danhof M
Brain Res
. 1998 Jan;
770(1-2):221-7.
PMID: 9372222
A large number of animal models has been proposed for the evaluation of the anticonvulsant effect of antiepileptic drugs. Various seizure patterns are produced and differences are frequently observed in...