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R A Hurta

Explore the profile of R A Hurta including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 29
Citations 228
Followers 0
Related Specialties
Biochemistry
Cell Biology
Physiology
Top 10 Co-Authors
J A Wright
A H Greenberg
S K Samuel
D Voskas
E A Turley
D N BURTON
O Yeung
J Lo
J Lee
A Huang
Published In
Biochem Cell Biol
J Cell Physiol
J Biol Chem
J Cell Biochem
Mol Cell Biochem
Affiliations
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Recent Articles
1.
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells
Yoon A, Hurta R
Mol Cell Biochem . 2001 Oct; 223(1-2):1-6. PMID: 11681709
The present study demonstrates alterations in the regulation of matrix metalloproteinase-2 (MMP-2) expression in response to insulin like growth factor-1 (IGF-1) in a H-ras transformed cell line, C3, which is...
2.
S-Adenosylmethionine decarboxylase gene expression is regulated by the cAMP signal transduction pathway in H-ras transformed fibrosarcoma cells capable of malignant progression
Hurta R
J Cell Biochem Suppl . 2001 Jul; Suppl 36:209-21. PMID: 11455586
The hypothesis that H-ras transformed cells contain alterations in signalling pathways important in controlling the expression of S-adenosylmethionine decarboxylase, (SAMDC) a highly regulated activity in the biosynthesis of polyamines was...
3.
Phorbol ester tumour promoter mediated altered expression and regulation of matrix metalloproteinase-2 in a H-ras transformed cell line capable of benign tumour formation
Yeung O, Hurta R
Mol Cell Biochem . 2001 Jul; 220(1-2):39-48. PMID: 11451381
The matrix metalloproteinases (MMPs) are thought to play key roles in tumour formation and malignant progression. The present study demonstrates alterations in the regulation of matrix metalloproteinase-2 (MMP-2) expression in...
4.
Altered matrix metalloproteinase expression associated with oncogene-mediated cellular transformation and metastasis formation
Baruch R, Melinscak H, Lo J, Liu Y, Yeung O, Hurta R
Cell Biol Int . 2001 Jun; 25(5):411-20. PMID: 11401328
Matrix metalloproteinase expression was examined in a series of mammalian cell lines of varying degrees of malignant progression. The expression of MMP-2 and MMP-9 was found to correlate with ras-mediated...
5.
Platelet-derived growth factor mediated altered expression and regulation of ornithine decarboxylase in H-ras-transformed cell lines
Voskas D, Kim M, Hurta R
Cell Signal . 2001 Jun; 13(6):401-9. PMID: 11384838
This study demonstrates a novel link between alterations in platelet-derived growth factor (PDGF) regulation of ornithine decarboxylase (ODC) expression during malignant conversion. H-ras-transformed cell lines exhibited PDGF-mediated alterations in ODC...
6.
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines
Voskas D, Mader R, Lee J, Hurta R
Biochem Cell Biol . 2001 Mar; 79(1):69-81. PMID: 11235918
Alterations in cellular growth are important in the progression of malignant disease. Cell growth regulation by tumour promoters can be complex. The present study demonstrates a novel link between alterations...
7.
Altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression and regulation in mouse fibroblasts transformed with oncogenes or constitutively active Mitogen-Activated Protein (MAP) kinase kinase
Hurta R
Mol Cell Biochem . 2001 Feb; 215(1-2):81-92. PMID: 11204459
In the present study, the expression and the regulation of ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC) was examined in a series of oncogene transformed cell lines. The expression of...
8.
Transformation by H-ras can result in aberrant regulation of ornithine decarboxylase gene expression by transforming growth factor-beta(1)
Hurta R, Lee J, Voskas D
J Cell Biochem . 2001 Feb; 81(1):39-55. PMID: 11180396
Inhibition of DNA synthesis and cell proliferation is frequently lost during malignant transformation and occasionally, tumour cell proliferation is actually stimulated by transforming growth factor beta(1) (TGF-beta(1)). The present study...
9.
Transforming growth factor beta1 selectively regulates ferritin gene expression in malignant H-ras-transformed fibrosarcoma cell lines
Lo J, Hurta R
Biochem Cell Biol . 2000 Sep; 78(4):527-35. PMID: 11012093
Transforming growth factor beta1 is an important growth regulator in many cell types, usually exerting a negative effect on cellular growth. Inhibition of DNA synthesis and cell proliferation is frequently...
10.
Insulin-mediated alterations in S-adenosylmethionine decarboxylase expression in H-ras transformed cells of varying degrees of malignancy
Bielecki D, Hurta R
Cell Signal . 2000 Sep; 12(7):451-6. PMID: 10989279
Cell growth regulation is a highly complex process. The present study demonstrates a novel link between alterations in insulin-mediated regulation during malignant conversion and the expression of S-adenosylmethionine decarboxylase, a...