R A Hurta
Overview
Explore the profile of R A Hurta including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
228
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Recent Articles
11.
Hurta R, Huang A, Wright J
J Cell Biochem
. 1996 Mar;
60(4):572-83.
PMID: 8707896
Cell growth regulation by fibroblast growth factors (FGFs) is highly complex. The present study demonstrates a novel link between alterations in bFGF regulation during malignant conversion and the expression of...
12.
Amara F, Hurta R, Huang A, Wright J
Cancer Res
. 1995 Oct;
55(20):4503-6.
PMID: 7553616
Mammalian ribonucleotide reductase is a highly regulated activity essential for DNA synthesis and repair. The activity and message levels of the enzyme are elevated in cells treated with the tumor...
13.
Chadee D, Taylor W, Hurta R, Allis C, Wright J, Davie J
J Biol Chem
. 1995 Aug;
270(34):20098-105.
PMID: 7650028
We compared the nucleosomal organization, histone H1 subtypes, and histone H1 phosphorylated isoforms of ras-transformed and parental 10T1/2 mouse fibroblasts. In agreement with previous studies, we found that ras-transformed mouse...
14.
Hurta R, Wright J
J Cell Biochem
. 1995 Mar;
57(3):543-56.
PMID: 7768988
Ribonucleotide reductase is a key rate-limiting and regulatory step in DNA synthesis and plays a crucial role in the coordination of DNA synthesis, DNA repair, and cell proliferation. The present...
15.
Hurta R, Wright J
J Cell Physiol
. 1994 Nov;
161(2):383-91.
PMID: 7525612
We have tested the hypothesis that H-ras transformed cells contain alterations in signal pathways important in controlling the expression of ornithine decarboxylase (ODC), the highly regulated rate-limiting activity in the...
16.
Hurta R, Wright J
J Cell Physiol
. 1994 Jan;
158(1):187-97.
PMID: 7505277
Ribonucleotide reductase is a highly regulated activity responsible for reducing ribonucleotides to deoxyribonucleotides, which are required for DNA synthesis and DNA repair. We have tested the hypothesis that malignant cell...
17.
Samuel S, Hurta R, Spearman M, Wright J, Turley E, Greenberg A
J Cell Biol
. 1993 Nov;
123(3):749-58.
PMID: 7693717
TGF-beta is a potent stimulator of motility in a variety of cell types. It has recently been shown that hyaluronan (HA) can directly promote locomotion of cells through interaction with...
18.
Hurta R, Greenberg A, Wright J
J Cell Physiol
. 1993 Aug;
156(2):272-9.
PMID: 8344985
Negative growth regulators such as the transforming growth factor beta (TGF-beta) family appear to be important inhibitors in most tissue types. However, inhibition of DNA synthesis and cell proliferation is...
19.
Hurta R, Wright J
Biochem Cell Biol
. 1992 Oct;
70(10-11):1081-7.
PMID: 1338411
A rapid elevation of ribonucleotide reductase activity was observed with BALB c/3T3 fibroblasts treated with 10 nM okadaic acid, a nonphorbol ester tumor promoter and protein phosphatase inhibitor. Northern blot...
20.
Hurta R, Greenberg A, Wright J
J Cell Physiol
. 1992 Sep;
152(3):529-35.
PMID: 1506411
Transforming growth factor-beta 1 (TGF-beta 1) stimulated DNA synthesis (3-fold) in BALBc/3T3 fibroblasts following 24 hours of growth factor exposure. Since ribonucleotide reductase is important for the coordination of DNA...