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Quentin Philippot

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Articles 49
Citations 4274
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Recent Articles
1.
Franco G, Le Guen P, Le Brun M, Philippot Q, Dupin C, Debray M, et al.
ERJ Open Res . 2024 Dec; 10(6). PMID: 39624383
https://bit.ly/3ClggYb.
2.
Rosain J, Le Voyer T, Liu X, Gervais A, Polivka L, Cederholm A, et al.
J Exp Med . 2024 Oct; 221(11). PMID: 39352576
Human inborn errors of thymic T cell tolerance underlie the production of autoantibodies (auto-Abs) neutralizing type I IFNs, which predispose to severe viral diseases. We analyze 131 female patients with...
3.
Arango-Franco C, Ogishi M, Unger S, Delmonte O, Orrego J, Yatim A, et al.
J Clin Invest . 2024 Oct; 134(19). PMID: 39352394
Infants with biallelic IL7R loss-of-function variants have severe combined immune deficiency (SCID) characterized by the absence of autologous T lymphocytes, but normal counts of circulating B and NK cells (T-B+NK+...
4.
Arias A, Neehus A, Ogishi M, Meynier V, Krebs A, Lazarov T, et al.
Nature . 2024 Aug; 633(8029):417-425. PMID: 39198650
Severe defects in human IFNγ immunity predispose individuals to both Bacillus Calmette-Guérin disease and tuberculosis, whereas milder defects predispose only to tuberculosis. Here we report two adults with recurrent pulmonary...
5.
Philippot Q, Rammaert B, Dauriat G, Daubin C, Schlemmer F, Costantini A, et al.
Heliyon . 2024 Jul; 10(13):e33231. PMID: 39035530
Background: Human metapneumovirus (hMPV) is one of the leading respiratory viruses. This prospective observational study aimed to describe the clinical features and the outcomes of hMPV-associated lower respiratory tract infections...
6.
Neehus A, Carey B, Landekic M, Panikulam P, Deutsch G, Ogishi M, et al.
Cell . 2024 May; 187(13):3460. PMID: 38776920
No abstract available.
7.
Hurley K, Ozaki M, Philippot Q, Galvin L, Crosby D, Kirwan M, et al.
EBioMedicine . 2024 May; 104:105135. PMID: 38718684
Interstitial lung diseases (ILDs) in adults and children (chILD) are a heterogeneous group of lung disorders leading to inflammation, abnormal tissue repair and scarring of the lung parenchyma often resulting...
8.
Momenilandi M, Levy R, Sobrino S, Li J, Lagresle-Peyrou C, Esmaeilzadeh H, et al.
Cell . 2024 May; 187(11):2817-2837.e31. PMID: 38701783
FMS-related tyrosine kinase 3 ligand (FLT3L), encoded by FLT3LG, is a hematopoietic factor essential for the development of natural killer (NK) cells, B cells, and dendritic cells (DCs) in mice....
9.
Brudon A, Legendre M, Mageau A, Bermudez J, Bonniaud P, Bouvry D, et al.
Eur Respir J . 2024 Apr; 63(5). PMID: 38575158
Background: Several rare surfactant-related gene (SRG) variants associated with interstitial lung disease are suspected to be associated with lung cancer, but data are missing. We aimed to study the epidemiology...
10.
Rosain J, Kiykim A, Michev A, Kendir-Demirkol Y, Rinchai D, Peel J, et al.
J Clin Immunol . 2024 Feb; 44(3):62. PMID: 38363432
Purpose: Inborn errors of IFN-γ immunity underlie Mendelian susceptibility to mycobacterial disease (MSMD). Twenty-two genes with products involved in the production of, or response to, IFN-γ and variants of which...