Quenna Wong
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Explore the profile of Quenna Wong including associated specialties, affiliations and a list of published articles.
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30
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2633
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Recent Articles
1.
Smith J, Wong Q, Hornsby W, Conomos M, Heavner B, Kullo I, et al.
ArXiv
. 2025 Feb;
PMID: 39990790
Sharing diverse genomic and other biomedical datasets is critical to advance scientific discoveries and their equitable translation to improve human health. However, data sharing remains challenging in the context of...
2.
de Vries P, Conomos M, Singh K, Nicholson C, Jain D, Hasbani N, et al.
Nat Cardiovasc Res
. 2024 May;
2(12):1159-1172.
PMID: 38817323
Coronary artery calcification (CAC) is a measure of atherosclerosis and a well-established predictor of coronary artery disease (CAD) events. Here we describe a genome-wide association study (GWAS) of CAC in...
3.
Kavousi M, Bos M, Barnes H, Lino Cardenas C, Wong D, Lu H, et al.
Nat Genet
. 2023 Sep;
55(10):1651-1664.
PMID: 37770635
Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts future symptomatic coronary artery disease (CAD). Identifying genetic risk factors for CAC may point to new therapeutic avenues for prevention....
4.
Brown B, Wang C, Kasela S, Aguet F, Nachun D, Taylor K, et al.
Cell Genom
. 2023 Aug;
3(8):100359.
PMID: 37601969
Multi-omics datasets are becoming more common, necessitating better integration methods to realize their revolutionary potential. Here, we introduce multi-set correlation and factor analysis (MCFA), an unsupervised integration method tailored to...
5.
Khan A, Gogarten S, McHugh C, Stilp A, Sofer T, Bowers M, et al.
Cell Genom
. 2022 Sep;
2(8).
PMID: 36119389
How race, ethnicity, and ancestry are used in genomic research has wide-ranging implications for how research is translated into clinical care and incorporated into public understanding. Correlation between race and...
6.
Wang Z, Emmerich A, Pillon N, Moore T, Hemerich D, Cornelis M, et al.
Nat Genet
. 2022 Sep;
54(9):1332-1344.
PMID: 36071172
Although physical activity and sedentary behavior are moderately heritable, little is known about the mechanisms that influence these traits. Combining data for up to 703,901 individuals from 51 studies in...
7.
Kelly T, Sun X, He K, Brown M, Gagliano Taliun S, Hellwege J, et al.
Hypertension
. 2022 Jun;
79(8):1656-1667.
PMID: 35652341
Background: The availability of whole-genome sequencing data in large studies has enabled the assessment of coding and noncoding variants across the allele frequency spectrum for their associations with blood pressure....
8.
Nakao T, Bick A, Taub M, Zekavat S, Uddin M, Niroula A, et al.
Sci Adv
. 2022 Apr;
8(14):eabl6579.
PMID: 35385311
Human genetic studies support an inverse causal relationship between leukocyte telomere length (LTL) and coronary artery disease (CAD), but directionally mixed effects for LTL and diverse malignancies. Clonal hematopoiesis of...
9.
Hu Y, Haessler J, Manansala R, Wiggins K, Moscati A, Beiser A, et al.
Stroke
. 2021 Nov;
53(3):875-885.
PMID: 34727735
Background And Purpose: Stroke is the leading cause of death and long-term disability worldwide. Previous genome-wide association studies identified 51 loci associated with stroke (mostly ischemic) and its subtypes among...
10.
Stilp A, Emery L, Broome J, Buth E, Khan A, Laurie C, et al.
Am J Epidemiol
. 2021 Apr;
190(10):1977-1992.
PMID: 33861317
Genotype-phenotype association studies often combine phenotype data from multiple studies to increase statistical power. Harmonization of the data usually requires substantial effort due to heterogeneity in phenotype definitions, study design,...