QueeLim Chng
Overview
Explore the profile of QueeLim Chng including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
587
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0
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Recent Articles
1.
Mishra S, Dabaja M, Akhlaq A, Pereira B, Marbach K, Rovcanin M, et al.
Elife
. 2023 Nov;
12.
PMID: 37975568
An animal's responses to environmental cues are critical for its reproductive program. Thus, a mechanism that allows the animal to sense and adjust to its environment should make for a...
2.
Blundell B, Sieben C, Manley S, Rosten E, Chng Q, Cox S
Front Bioinform
. 2022 Oct;
1:740342.
PMID: 36303741
Understanding the structure of a protein complex is crucial in determining its function. However, retrieving accurate 3D structures from microscopy images is highly challenging, particularly as many imaging modalities are...
3.
Patel D, Diana G, Entchev E, Zhan M, Lu H, Chng Q
Cell Rep
. 2020 Dec;
33(12):108521.
PMID: 33357442
Responsiveness to external cues is a hallmark of biological systems. In complex environments, it is crucial for organisms to remain responsive to specific inputs even as other internal or external...
4.
Wu T, Duan F, Yang W, Liu H, Caballero A, Fernandes De Abreu D, et al.
Neuron
. 2019 Nov;
104(6):1095-1109.e5.
PMID: 31676170
Social environment modulates learning through unknown mechanisms. Here, we report that a pheromone mixture that signals overcrowding inhibits C. elegans from learning to avoid pathogenic bacteria. We find that learning...
5.
Javer A, Currie M, Lee C, Hokanson J, Li K, Martineau C, et al.
Nat Methods
. 2018 Sep;
15(9):645-646.
PMID: 30171234
No abstract available.
6.
Genetic dissection of neuropeptide cell biology at high and low activity in a defined sensory neuron
Laurent P, Chng Q, Jospin M, Chen C, Lorenzo R, De Bono M
Proc Natl Acad Sci U S A
. 2018 Jul;
115(29):E6890-E6899.
PMID: 29959203
Neuropeptides are ubiquitous modulators of behavior and physiology. They are packaged in specialized secretory organelles called dense core vesicles (DCVs) that are released upon neural stimulation. Unlike synaptic vesicles, which...
7.
Patel D, Diana G, Entchev E, Zhan M, Lu H, Chng Q
J Vis Exp
. 2017 Sep;
(126).
PMID: 28872114
Sensory systems allow animals to detect, process, and respond to their environment. Food abundance is an environmental cue that has profound effects on animal physiology and behavior. Recently, we showed...
8.
Diana G, Patel D, Entchev E, Zhan M, Lu H, Chng Q
Elife
. 2017 Feb;
6.
PMID: 28166866
Neuroendocrine circuits encode environmental information via changes in gene expression and other biochemical activities to regulate physiological responses. Previously, we showed that TGFβ and tryptophan hydroxylase expression in specific neurons...
9.
Entchev E, Patel D, Zhan M, Steele A, Lu H, Chng Q
Elife
. 2015 May;
4:e06259.
PMID: 25962853
How the nervous system internally represents environmental food availability is poorly understood. Here, we show that quantitative information about food abundance is encoded by combinatorial neuron-specific gene-expression of conserved TGFβ...
10.
Zhan M, Crane M, Entchev E, Caballero A, Fernandes De Abreu D, Chng Q, et al.
PLoS Comput Biol
. 2015 Apr;
11(4):e1004194.
PMID: 25910032
Quantitative imaging has become a vital technique in biological discovery and clinical diagnostics; a plethora of tools have recently been developed to enable new and accelerated forms of biological investigation....