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Qizhuang Ye

Explore the profile of Qizhuang Ye including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 78
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Recent Articles
1.
Yang B, Mei Y, Li Q, Zhang M, Tang H, Liu T, et al.
Future Med Chem . 2021 Mar; 13(11):959-974. PMID: 33783231
There is an urgent need for new antibiotics and alternative strategies to combat bacterial pathogens. Molecular docking, antibacterial evaluation and , cytotoxicity assessment and enzyme inhibition analyses were performed. Compound...
2.
Zhan J, Jia H, Semchenko E, Bian Y, Zhou A, Li Z, et al.
FASEB J . 2018 Sep; 33(2):2095-2104. PMID: 30260702
Bacterial infection is one of the leading causes of death in young, elderly, and immune-compromised patients. The rapid spread of multi-drug-resistant (MDR) bacteria is a global health emergency and there...
3.
Zhang Q, Zeng S, Zhang Y, Zhang Y, Ding D, Ye Q, et al.
EMBO Mol Med . 2012 Feb; 4(4):298-312. PMID: 22331558
Although ∼50% of all types of human cancers harbour wild-type TP53, this p53 tumour suppressor is often deactivated through a concerted action by its abnormally elevated suppressors, MDM2, MDMX or...
4.
Mi Ahn Y, Vogeti L, Liu C, Santhapuram H, White J, Vasandani V, et al.
Bioorg Med Chem . 2006 Nov; 15(2):702-13. PMID: 17123821
The design and synthesis of a small library of 8-amidoflavone, 8-sulfonamidoflavone, 8-amido-7-hydroxyflavone, and heterocyclic analogues of flavopiridol is reported. The potential activity of these compounds as kinase inhibitors was evaluated...
5.
Ma D, Jiang Y, Chen F, Gong L, Ding K, Xu Y, et al.
J Med Chem . 2006 Jan; 49(2):456-8. PMID: 16420030
The synthesis and matrix metalloproteinase (MMP) inhibitory activity of a series of gamma-keto carboxylic acids are described. Among nine MMP isozymes tested, compound 1j displays selective inhibition of MMP-2, -9,...
6.
Ma D, Wu W, Yang G, Li J, Li J, Ye Q
Bioorg Med Chem Lett . 2003 Dec; 14(1):47-50. PMID: 14684295
The synthesis and MMP inhibitory activity of a series of tetrahydroisoquinoline based sulfonamide hydroxamates are described. In nine MMPs tested, most of the compounds display potent inhibition activity except for...