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Qisheng Zheng

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Articles 39
Citations 376
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Recent Articles
1.
Du L, Lu H, Qiao X, Zhang Y, Hou L, Yu X, et al.
Immunol Lett . 2024 Mar; 267:106856. PMID: 38537718
Multifunctional CD4 T helper 1 (Th1) cells, producing IFN-γ, TNF-α and IL-2, define a correlate of vaccine-mediated protection against intracellular infection. In our previous study, we found that CVC1302 in...
2.
Luo X, Yu S, Liu B, Zheng Q, Zhou X, An K, et al.
Transplantation . 2024 Mar; 108(9):e207-e217. PMID: 38499504
Background: Uterus transplantation (UTx) is an emerging treatment for uterine factor infertility. Determining the maximum tolerable cold ischemia time is crucial for successful UTx. However, the limit for cold ischemia...
3.
Yao H, Zhang J, Zheng Q, Zeng X, Huang H, Ling Z, et al.
Arch Pharm (Weinheim) . 2024 Mar; 357(6):e2300753. PMID: 38442328
Selective inhibition of Janus kinase 3 (JAK3) is a promising strategy for the treatment of autoimmune diseases. Based on the discovery of a hydrophobic pocket unutilized between the lead compound...
4.
Hou W, Huang L, Huang H, Liu S, Dai W, Tang J, et al.
Molecules . 2024 Jan; 29(2). PMID: 38276618
Sinomenine, an isoquinoline alkaloid extracted from the roots and stems of , has been extensively studied for its derivatives as bioactive agents. This review concentrates on the research advancements in...
5.
Lu H, Yu X, Hou L, Zhang Y, Li L, Qiao X, et al.
Vaccines (Basel) . 2024 Jan; 12(1). PMID: 38250899
Monocytes (Mos) are believed to play important roles during the generation of immune response. In our previous study, CVC1302, a complex of PRRs agonists, was demonstrated to recruit Mo into...
6.
Yu X, Zhang Y, Hou L, Qiao X, Zhang Y, Cheng H, et al.
Vaccines (Basel) . 2023 Nov; 11(11). PMID: 38006050
This study found a higher percentage of CD8 T cells in piglets immunized with a CVC1302-adjuvanted inactivated foot-and-mouth disease virus (FMDV) vaccine. We wondered whether the CVC1302-adjuvanted inactivated FMDV vaccine...
7.
Cheng H, Yang L, Hou L, Cai Z, Yu X, Du L, et al.
Int Immunopharmacol . 2023 Apr; 119:110140. PMID: 37116343
As the most potent professional antigen presenting cells, dendritic cells (DCs) have been targeted in strategies to enhance vaccination efficacy. To date, targeted delivery has been mainly used for cancer...
8.
Liu S, Wu J, Lu X, Guo C, Zheng Q, Wang Y, et al.
Exp Cell Res . 2023 Apr; 428(1):113613. PMID: 37100369
Colorectal cancer (CRC) is the second most common cause of cancer-related mortality and lies third in terms of morbidity due to the limited number of effective druggable targets. Since cancer...
9.
Hou L, Yu X, Zhang Y, Du L, Zhang Y, Cheng H, et al.
Front Immunol . 2022 Apr; 13:845680. PMID: 35432301
Cyclic dimeric guanosine monophosphate (c-di-GMP) is a bacterial second messenger with immunomodulatory activities in mice, suggesting potential applications as a vaccine immunopotentiator or therapeutic agent. In this study, we evaluated...
10.
Du L, Hou L, Yu X, Cheng H, Chen J, Zheng Q, et al.
Front Immunol . 2021 Dec; 12:697292. PMID: 34867941
Ideally, a vaccine should provide life-long protection following a single administered dose. In our previous study, the immunopotentiator CVC1302, which contains pattern- recognition receptor (PRR) agonists, was demonstrated to prolong...