Qingzhe Wu
Overview
Explore the profile of Qingzhe Wu including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
270
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0
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Recent Articles
1.
Jin Y, Wu Y, Reuben A, Zhu L, Gay C, Wu Q, et al.
Cell Discov
. 2024 Dec;
10(1):126.
PMID: 39702462
No abstract available.
2.
Jin Y, Wu Y, Reuben A, Zhu L, Gay C, Wu Q, et al.
Cell Discov
. 2024 Sep;
10(1):93.
PMID: 39231924
Small cell lung cancer (SCLC) is an aggressive pulmonary neuroendocrine malignancy featured by cold tumor immune microenvironment (TIME), limited benefit from immunotherapy, and poor survival. The spatial heterogeneity of TIME...
3.
Liu Y, Wu Q, Jiang B, Hou T, Wu C, Wu M, et al.
Mol Cancer Res
. 2024 Mar;
22(7):613-624.
PMID: 38512021
Small cell lung cancer (SCLC) is an aggressive and lethal malignancy. Achaete-scute homolog 1 (ASCL1) is essential for the initiation of SCLC in mice and the development of pulmonary neuroendocrine...
4.
Wu Q, Guo J, Liu Y, Zheng Q, Li X, Wu C, et al.
Sci Adv
. 2021 Oct;
7(40):eabg1850.
PMID: 34597132
Small cell lung cancer (SCLC) has a high degree of plasticity and is characterized by a remarkable response to chemotherapy followed by the development of resistance. Here, we use a...
5.
Lu J, Hu Z, Deng Y, Wu Q, Wu M, Song H
J Biol Chem
. 2021 Feb;
296:100400.
PMID: 33571521
The Hippo pathway is an evolutionarily conserved signaling pathway that controls organ size in animals via the regulation of cell proliferation and apoptosis. It consists of a kinase cascade, in...
6.
Wu S, Zhang Q, Zhang F, Meng F, Liu S, Zhou R, et al.
Nat Cell Biol
. 2019 Jul;
21(8):1027-1040.
PMID: 31332347
Sensing cytosolic DNA through the cGAS-STING pathway constitutes a widespread innate immune mechanism to monitor cellular damage and microbial invasion. Evading this surveillance is crucial in tumorigenesis, but the process...
7.
Wu A, Wu Q, Deng Y, Liu Y, Lu J, Liu L, et al.
EMBO J
. 2018 Nov;
38(1).
PMID: 30396996
Targeting immune checkpoints, such as PD-L1 and its receptor PD-1, has opened a new avenue for treating cancers. Understanding the regulatory mechanism of PD-L1 and PD-1 will improve the clinical...
8.
Lu J, Liu L, Zheng M, Li X, Wu A, Wu Q, et al.
Oncogene
. 2018 Apr;
37(28):3864-3878.
PMID: 29662197
Hedgehog (Hh) pathway plays a pivotal role in diverse aspects of development and postnatal physiology. Perturbation of Hh signaling and activation of GLI1 (glioma-associated oncogene 1), a dedicated transcription factor...
9.
Liu L, Lu J, Li X, Wu A, Wu Q, Zhao M, et al.
Cell Rep
. 2018 Mar;
22(12):3277-3291.
PMID: 29562183
Intracellular transport of membranous organelles and protein complexes to various destinations is fundamental to signaling transduction and cellular function. The cytoplasmic dynein motor and its regulatory proteins LIS1 and NDE1...
10.
Li X, Liu L, Li R, Wu A, Lu J, Wu Q, et al.
J Biol Chem
. 2018 Feb;
293(14):5160-5171.
PMID: 29475944
The liver is a major organ in lipid metabolism, and its malfunction leads to various diseases. Nonalcoholic fatty liver disease, the most common chronic liver disorder in developed countries, is...