Qingmin Ruan
Overview
Explore the profile of Qingmin Ruan including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
159
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0
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Recent Articles
1.
Ni Y, Wang Y, Shi X, Yu F, Ruan Q, Tian N, et al.
EMBO Rep
. 2024 Nov;
25(12):5316-5330.
PMID: 39501049
Retrons, found in bacteria and used for defense against phages, generate a unique molecule known as multicopy single-stranded DNA (msDNA). This msDNA mimics Okazaki fragments during DNA replication, making it...
2.
Ruan Q, Harrington A, Caldwell K, Caldwell G, Standaert D
Neurobiol Dis
. 2009 Oct;
37(2):330-8.
PMID: 19850127
VPS41 is a protein identified as a potential therapeutic target for Parkinson's disease (PD) as a result of a high-throughput RNAi screen in Caenorhabditis elegans. VPS41 has a plausible mechanistic...
3.
Caldwell K, Tucci M, Armagost J, Hodges T, Chen J, Memon S, et al.
PLoS One
. 2009 Oct;
4(10):e7227.
PMID: 19806188
Parkinson disease (PD) involves progressive neurodegeneration, including loss of dopamine (DA) neurons from the substantia nigra. Select genes associated with rare familial forms of PD function in cellular pathways, such...
4.
Ruan Q, Tucholski J, Gundemir S, Johnson Voll G
Int J Clin Exp Med
. 2008 Dec;
1(3):248-59.
PMID: 19079660
Type 2 transglutaminase (TG2) is an acyltransferase, which also undergoes a GTP-binding/GTPase cycle, with guanine nucleotide and calcium binding reciprocally regulating its transamidation (TG) activity. TG2 is expressed ubiquitously throughout...
5.
Ruan Q, Quintanilla R, Johnson G
J Neurochem
. 2007 Apr;
102(1):25-36.
PMID: 17403029
Huntington's disease (HD), which is caused by an expanded polyglutamine tract in huntingtin (htt), is characterized by extensive loss of striatal neurons. The dysregulation of type 2 transglutaminase (TG2) has...
6.
Ruan Q, Johnson G
Front Biosci
. 2006 Nov;
12:891-904.
PMID: 17127346
Type 2 transglutaminase (TG2) is a calcium-dependent acyltransferase which also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. As an enzyme...
7.
Ruan Q, Lesort M, MacDonald M, Johnson G
Hum Mol Genet
. 2004 Feb;
13(7):669-81.
PMID: 14962977
Extensive striatal neuronal loss occurs in Huntington's disease (HD), which is caused by an expanded polyglutamine tract in huntingtin (htt). Evidence suggests that mutant htt directly or indirectly compromises mitochondrial...