Qingfen Zhu
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Explore the profile of Qingfen Zhu including associated specialties, affiliations and a list of published articles.
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10
Citations
63
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Recent Articles
1.
Zhao Z, Song X, Wang Y, Yu L, Huang G, Li Y, et al.
Cell Death Differ
. 2024 Jun;
31(11):1410-1421.
PMID: 38918620
Mitochondrial dysfunction plays a pivotal role in the pathogenesis of Parkinson's disease (PD). As a mitochondrial governor, voltage-dependent anion channel 1 (VDAC1) is critical for cell survival and death signals...
2.
Zheng S, Li Y, Song X, Wu M, Yu L, Huang G, et al.
J Neuroinflammation
. 2023 Nov;
20(1):281.
PMID: 38012669
Background: Inflammatory response triggered by innate immunity plays a pivotal element in the progress of ischemic stroke. Receptor-interacting kinase 2 (RIP2) is implicated in maintaining immunity homeostasis and regulating inflammatory...
3.
Ma S, Tian Y, Peng J, Chen C, Peng X, Zhao F, et al.
Sci Transl Med
. 2023 Nov;
15(722):eadg6752.
PMID: 37967204
T cell immunoglobulin and mucin-containing molecule 3 (Tim-3), expressed in dysfunctional and exhausted T cells, has been widely acknowledged as a promising immune checkpoint target for tumor immunotherapy. Here, using...
4.
Liu S, Lyu J, Li Q, Wu X, Yang Y, Huo G, et al.
J Toxicol Pathol
. 2022 Feb;
35(1):25-36.
PMID: 35221493
Lymphoma is the third most common cancer diagnosed in children, and T-cell lymphoma has the worst prognosis based on clinical observations. To date, a lymphoma model with uniform penetrance has...
5.
Li E, Lin N, Hao R, Fan X, Lin L, Hu G, et al.
Toxicol Rep
. 2020 Oct;
7:1402-1411.
PMID: 33102144
Aim: Excessive exposure to 5-hydroxymethylfurfural (5-HMF), which is a common impurity in various sugar-containing products, induces serious side effects. Our previous study revealed that 5-HMF exerted immune sensitizing potential when...
6.
Jing W, Guo X, Wang G, Bi Y, Han L, Zhu Q, et al.
Int Immunopharmacol
. 2019 Dec;
78:106012.
PMID: 31865052
Macrophages are recognized as one of the major cell types in tumor microenvironment, and macrophage infiltration has been predominantly associated with poor prognosis among patients with breast cancer. Using the...
7.
Wei X, Zhu Q, Liu N, Xu L, Wei S, Fan Z, et al.
Front Pharmacol
. 2019 Oct;
10:1096.
PMID: 31611791
Zhenlong Xingnao Capsule (ZXC) is a Tibetan medicine used to treat ischemic stroke. In this study, we determined the and effects of ZXC on reactive oxygen species (ROS) in a...
8.
Zhu Q, Li T, Wei X, Li J, Wang W
Drug Chem Toxicol
. 2013 Nov;
37(3):311-5.
PMID: 24224725
It is important to establish the safety of impurities in drug substances or drug products. The assessment of genotoxicity of impurities and the determination of acceptable limits for genotoxic impurities...
9.
Zhu Q, Li T, Li J, Guo M, Wang W, Zhang X
Toxicol Mech Methods
. 2011 Nov;
22(3):225-30.
PMID: 22087570
Impurities in drug substances and drug products generally do not have beneficial effects and may impose a risk without associated benefit. Levofloxacin n-oxide is an impurity isolated from levofloxacin. However...
10.
Li X, Li X, Zhou Y, Liu Y, Guo M, Zhu Q, et al.
J Pharm Sci
. 2009 Sep;
99(4):1790-9.
PMID: 19774661
The purpose of this work was to investigate feasibility of a promising topical drug delivery system (TDDS) for sinomenine hydrochloride (SMH), extracted from the Chinese medicinal plant sinomenine acutum and...