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Qiantao Zheng

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Articles 19
Citations 420
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Recent Articles
1.
Pan J, Chui L, Liu T, Zheng Q, Liu X, Liu L, et al.
Microbiol Spectr . 2023 Jan; 11(1):e0354022. PMID: 36688695
The relationship between the host gut microbiota and obesity has been well documented in humans and mice; however, few studies reported the association between the gut microbiota and fat deposition...
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Kim M, Li Y, Zheng Q, Jiang L, Myers Jr M, Wu W, et al.
J Clin Invest . 2022 Dec; 133(4). PMID: 36512408
Leptin exerts its biological actions by activating the long-form leptin receptor (LepRb). LepRb signaling impairment and leptin resistance are believed to cause obesity. The transcription factor Slug - also known...
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Song R, Wang Y, Zheng Q, Yao J, Cao C, Wang Y, et al.
Sci China Life Sci . 2022 Jan; 65(4):739-752. PMID: 35060075
The precise and simultaneous acquisition of multiple beneficial alleles in the genome is in great demand for the development of elite pig breeders. Cytidine base editors (CBEs) that convert C:G...
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Gu P, Hui X, Zheng Q, Gao Y, Jin L, Jiang W, et al.
Sci Adv . 2021 Dec; 7(50):eabl4024. PMID: 34878840
Mitochondrial uncoupling protein 1 (UCP1) is the hallmark of brown adipocytes responsible for cold- and diet-induced thermogenesis. Here, we report a previously unidentified role of UCP1 in maintaining vascular health...
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Wang Y, Bi D, Qin G, Song R, Yao J, Cao C, et al.
Front Genet . 2020 Dec; 11:592623. PMID: 33304388
Pig is an important agricultural economic animal, providing large amount of meat products. With the development of functional genomics and bioinformatics, lots of genes and functional single nucleotide polymorphisms (SNPs)...
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Pan J, Tao C, Cao C, Zheng Q, Lam S, Shui G, et al.
Biochim Biophys Acta Mol Cell Biol Lipids . 2019 Jul; 1864(10):1375-1383. PMID: 31271850
Uncoupling protein 1 (UCP1) plays a key role in nonshivering thermogenesis and is involved in the pathogenesis of obesity. In a previous study, we generated adipocyte-specific UCP1 knock-in (UCP1-KI) pigs,...
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Wang X, Cao C, Li Y, Hai T, Jia Q, Zhang Y, et al.
J Mol Cell Biol . 2019 Mar; 11(12):1029-1041. PMID: 30925591
Harlequin ichthyosis (HI) is a severe genetic skin disorder and caused by mutation in the ATP-binding cassette A12 (ABCA12) gene. The retinoid administration has dramatically improved long-term survival of HI,...
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Cao C, Zhang Y, Jia Q, Wang X, Zheng Q, Zhang H, et al.
Dis Model Mech . 2019 Jan; 12(1). PMID: 30651277
Pigs share many similarities with humans in terms of anatomy, physiology and genetics, and have long been recognized as important experimental animals in biomedical research. Using an N-ethyl-N-nitrosourea (ENU) mutagenesis...
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Zhang H, Huang J, Li Z, Qin G, Zhang N, Hai T, et al.
EMBO Mol Med . 2018 Nov; 10(12). PMID: 30446498
Porcine-derived xenogeneic sources for transplantation are a promising alternative strategy for providing organs for treatment of end-stage organ failure in human patients because of the shortage of human donor organs....