Qianmu Yuan
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Explore the profile of Qianmu Yuan including associated specialties, affiliations and a list of published articles.
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15
Citations
153
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Recent Articles
1.
Zhu M, Song Y, Yuan Q, Yang Y
Commun Biol
. 2024 Dec;
7(1):1709.
PMID: 39739114
Proteins derived from microorganisms that survive in the harshest environments on Earth have stable activity under extreme conditions, providing rich resources for industrial applications and enzyme engineering. Due to the...
2.
Song Y, Yuan Q, Chen S, Zeng Y, Zhao H, Yang Y
Nat Commun
. 2024 Sep;
15(1):8180.
PMID: 39294165
Enzymes are crucial in numerous biological processes, with the Enzyme Commission (EC) number being a commonly used method for defining enzyme function. However, current EC number prediction technologies have not...
3.
Rao J, Xie J, Yuan Q, Liu D, Wang Z, Lu Y, et al.
Nat Commun
. 2024 May;
15(1):4476.
PMID: 38796523
Protein functions are characterized by interactions with proteins, drugs, and other biomolecules. Understanding these interactions is essential for deciphering the molecular mechanisms underlying biological processes and developing new therapeutic strategies....
4.
Yuan Q, Tian C, Song Y, Ou P, Zhu M, Zhao H, et al.
Nucleic Acids Res
. 2024 May;
52(W1):W248-W255.
PMID: 38738636
Knowledge of protein function is essential for elucidating disease mechanisms and discovering new drug targets. However, there is a widening gap between the exponential growth of protein sequences and their...
5.
Yuan Q, Tian C, Yang Y
Elife
. 2024 Apr;
13.
PMID: 38630609
Revealing protein binding sites with other molecules, such as nucleic acids, peptides, or small ligands, sheds light on disease mechanism elucidation and novel drug design. With the explosive growth of...
6.
Qin Z, Wang R, Hou P, Zhang Y, Yuan Q, Wang Y, et al.
J Exp Med
. 2024 Feb;
221(3).
PMID: 38324068
TH17 differentiation is critically controlled by "signal 3" of cytokines (IL-6/IL-23) through STAT3. However, cytokines alone induced only a moderate level of STAT3 phosphorylation. Surprisingly, TCR stimulation alone induced STAT3...
7.
Fang Y, Jiang Y, Wei L, Ma Q, Ren Z, Yuan Q, et al.
Bioinformatics
. 2023 Nov;
39(12).
PMID: 38015872
Motivation: Identifying the functional sites of a protein, such as the binding sites of proteins, peptides, or other biological components, is crucial for understanding related biological processes and drug design....
8.
Wang J, Chen S, Yuan Q, Chen J, Li D, Wang L, et al.
J Comput Chem
. 2023 Nov;
45(8):436-445.
PMID: 37933773
Solubility is one of the most important properties of protein. Protein solubility can be greatly changed by single amino acid mutations and the reduced protein solubility could lead to diseases....
9.
Song Y, Yuan Q, Zhao H, Yang Y
Brief Bioinform
. 2023 Oct;
24(6).
PMID: 37824738
The interactions between nucleic acids and proteins are important in diverse biological processes. The high-quality prediction of nucleic-acid-binding sites continues to pose a significant challenge. Presently, the predictive efficacy of...
10.
Song Y, Yuan Q, Chen S, Chen K, Zhou Y, Yang Y
Brief Bioinform
. 2023 May;
24(4).
PMID: 37204193
Determining intrinsically disordered regions of proteins is essential for elucidating protein biological functions and the mechanisms of their associated diseases. As the gap between the number of experimentally determined protein...