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Pyeonghwa Jeong

Explore the profile of Pyeonghwa Jeong including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 69
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Recent Articles
11.
Kwak S, Lim W, Hao A, Mashalidis E, Kwon D, Jeong P, et al.
Eur J Med Chem . 2021 Feb; 215:113272. PMID: 33607457
Antibiotic resistance is one of the most challenging global health issues and presents an urgent need for the development of new antibiotics. In this regard, phospho-MurNAc-pentapeptide translocase (MraY), an essential...
12.
Lee H, Jeong P, Moon Y, Choi J, Heo J, Kim Y, et al.
Pharmaceuticals (Basel) . 2021 Jan; 14(1). PMID: 33419162
Rearranged during transfection (RET), a receptor tyrosine kinase, is activated by glial cell line-derived neurotrophic factor family ligands. Chromosomal rearrangement or point mutations in are observed in patients with papillary...
13.
Jeong P, Moon Y, Lee J, Lee S, Park J, Lee J, et al.
Eur J Med Chem . 2020 Apr; 195:112205. PMID: 32272419
FMS-like receptor tyrosine kinase-3 (FLT3) is expressed on acute leukemia cells and is implicated in the survival, proliferation and differentiation of hematopoietic cells in most acute myeloid leukemia (AML) patients....
14.
Kim W, Jeong P, Kim S, Cho H, Lee J, Seo S, et al.
Data Brief . 2019 Sep; 25:104373. PMID: 31489353
This article contains chemical characterization and biological activity data for a novel indirubin derivative, termed LDD-1819. The detailed synthesis procedure and associated NMR data are presented. The concentration-dependent inhibition data...
15.
Jeong P, Kim S, Li Q, Oh S, Son S, Chen G, et al.
ChemMedChem . 2019 Jul; 14(20):1783-1794. PMID: 31359587
G -protein-biased agonists with minimal β-arrestin recruitment represent opportunities to overcome the serious adverse effects of human mu opioid receptor (μ-OR) agonists and developing alternative and safe treatments for pain....
16.
Kim W, Jeong P, Kim S, Cho H, Lee J, Seo S, et al.
Bioorg Med Chem . 2019 Jun; 27(13):2923-2934. PMID: 31147141
Indirubin-based compounds affect diverse biological processes, such as inflammation and angiogenesis. In this study, we tested a novel indirubin derivative, LDD-1819 (2-((((2Z,3E)-5-hydroxy-5'-nitro-2'-oxo-[2,3'-biindolinylidene]-3-ylidene)amino)oxy)ethan-1-aminium chloride) for two major biological activities: cell plasticity...
17.
Lee H, Lee J, Jeong P, Choi J, Baek J, Ahn S, et al.
Oncotarget . 2018 May; 9(28):20219. PMID: 29733074
[This corrects the article DOI: 10.18632/oncotarget.23221.].
18.
Lee H, Lee J, Jeong P, Choi J, Baek J, Ahn S, et al.
Oncotarget . 2018 Feb; 9(1):924-936. PMID: 29416667
FMS-like receptor tyrosine kinase-3 (FLT3) belongs to the family of receptor tyrosine kinase (RTK), and the FLT3 mutation is observed in 1/3 of all acute myeloid leukemia (AML) patients. Potential...
19.
Kim B, Cho J, Jeong P, Lee Y, Lim J, Park K, et al.
FEBS Lett . 2015 May; 589(15):1795-801. PMID: 26022398
Coxsackievirus B3 is the main cause of human viral myocarditis and cardiomyopathy. Virally encoded Coxsackievirus 3C protease (3C(pro)) plays an essential role in viral proliferation. Here, benserazide was discovered as...