Purnendu Bhowmik
Overview
Explore the profile of Purnendu Bhowmik including associated specialties, affiliations and a list of published articles.
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5
Citations
30
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Recent Articles
1.
Shanbhag A, Bhowmik P
Yale J Biol Med
. 2024 Jul;
97(2):179-204.
PMID: 38947111
Aldo-keto reductases (AKRs) are a superfamily of promiscuous enzymes that have been chiseled by evolution to act as catalysts for numerous regulatory pathways in humans. However, they have not lost...
2.
Bhowmik P, Bharatham N, Murakami S, Ramachandran V, Datta S
Res Microbiol
. 2023 Feb;
174(4):104039.
PMID: 36738814
OqxB belongs to the RND (Resistance-Nodulation-Division) efflux pump family, recognized widely as a major contributor towards enhancing antimicrobial resistance. It is known to be predominantly present in all Klebsiella spp....
3.
Bhowmik P, Rajagopal S, Hmar R, Singh P, Saxena P, Amar P, et al.
ACS Synth Biol
. 2022 Jan;
11(2):713-731.
PMID: 35025506
Using as the representative biofilm former, we report here the development of an in silico model built by simulating events that transform a free-living bacterial entity into self-encased multicellular biofilms....
4.
Bharatham N, Bhowmik P, Aoki M, Okada U, Sharma S, Yamashita E, et al.
Nat Commun
. 2021 Sep;
12(1):5400.
PMID: 34518546
OqxB is an RND (Resistance-Nodulation-Division) efflux pump that has emerged as a factor contributing to the antibiotic resistance in Klebsiella pneumoniae. OqxB underwent horizontal gene transfer and is now seen...
5.
Hameed P S, Bharatham N, Katagihallimath N, Sharma S, Nandishaiah R, Shanbhag A, et al.
Sci Rep
. 2018 May;
8(1):7263.
PMID: 29740005
The mechanism of efflux is a tour-de-force in the bacterial armoury that has thwarted the development of novel antibiotics. We report the discovery of a novel chemical series with potent...