Sreenath Rajagopal
Overview
Explore the profile of Sreenath Rajagopal including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
28
Followers
0
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Recent Articles
1.
Hameed P S, Kotakonda H, Sharma S, Nandishaiah R, Katagihallimath N, Rao R, et al.
Nat Commun
. 2025 Feb;
16(1):2082.
PMID: 40021680
No abstract available.
2.
Hameed P S, Kotakonda H, Sharma S, Nandishaiah R, Katagihallimath N, Rao R, et al.
Nat Commun
. 2025 Jan;
16(1):625.
PMID: 39805821
No abstract available.
3.
Hameed P S, Kotakonda H, Sharma S, Nandishaiah R, Katagihallimath N, Rao R, et al.
Nat Commun
. 2024 Sep;
15(1):8202.
PMID: 39294149
The global crisis of antimicrobial resistance (AMR) necessitates the development of broad-spectrum antibacterial drugs effective against multi-drug resistant (MDR) pathogens. BWC0977, a Novel Bacterial Topoisomerase Inhibitor (NBTI) selectively inhibits bacterial...
4.
Shanbhag A, Rajagopal S, Ghatak A, Katagihallimath N, Subramanian R, Datta S
Biochem J
. 2023 Jun;
480(13):975-997.
PMID: 37335080
Enzymes are either specific or promiscuous catalysts in nature. The latter is portrayed by protein families like CYP450Es, Aldo-ketoreductases and short/medium-chain dehydrogenases which participate in detoxification or secondary metabolite production....
5.
Rajagopal S, Hmar R, Mookherjee D, Ghatak A, Shanbhag A, Katagihallimath N, et al.
ACS Synth Biol
. 2022 Jul;
11(8):2672-2684.
PMID: 35801944
Flux balance analysis (FBA) and ordinary differential equation models have been instrumental in depicting the metabolic functioning of a cell. Nevertheless, they demonstrate a population's average behavior (summation of individuals),...
6.
Shanbhag A, Ghatak A, Rajagopal S
Biotechnol Appl Biochem
. 2022 Jun;
70(2):537-552.
PMID: 35751426
There are three prominent alcohol dehydrogenases superfamilies: short-chain, medium-chain, and iron-containing alcohol dehydrogenases (FeADHs). Many members are valuable catalysts for producing industrially relevant products such as active pharmaceutical intermediates, chiral...
7.
Bhowmik P, Rajagopal S, Hmar R, Singh P, Saxena P, Amar P, et al.
ACS Synth Biol
. 2022 Jan;
11(2):713-731.
PMID: 35025506
Using as the representative biofilm former, we report here the development of an in silico model built by simulating events that transform a free-living bacterial entity into self-encased multicellular biofilms....
8.
Bharatham N, Bhowmik P, Aoki M, Okada U, Sharma S, Yamashita E, et al.
Nat Commun
. 2021 Sep;
12(1):5400.
PMID: 34518546
OqxB is an RND (Resistance-Nodulation-Division) efflux pump that has emerged as a factor contributing to the antibiotic resistance in Klebsiella pneumoniae. OqxB underwent horizontal gene transfer and is now seen...