Priyadharshini Arunachalam
Overview
Explore the profile of Priyadharshini Arunachalam including associated specialties, affiliations and a list of published articles.
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8
Citations
457
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Recent Articles
1.
Jensen M, Muller C, Schwedhelm E, Arunachalam P, Gelderblom M, Magnus T, et al.
Int J Mol Sci
. 2020 Mar;
21(5).
PMID: 32182846
l-arginine:glycine amidinotransferase (AGAT) and its metabolites homoarginine (hArg) and creatine have been linked to stroke pathology in both human and mouse studies. However, a comprehensive understanding of the underlying molecular...
2.
Gelderblom M, Gallizioli M, Ludewig P, Thom V, Arunachalam P, Rissiek B, et al.
Stroke
. 2017 Dec;
49(1):155-164.
PMID: 29212740
Background And Purpose: Inflammatory mechanisms can exacerbate ischemic tissue damage and worsen clinical outcome in patients with stroke. Both αβ and γδ T cells are established mediators of tissue damage...
3.
Arunachalam P, Ludewig P, Melich P, Arumugam T, Gerloff C, Prinz I, et al.
Stroke
. 2017 Jun;
48(7):1957-1965.
PMID: 28611085
Background And Purpose: Immune-mediated tissue damage after stroke evolves within the first days, and lymphocytes contribute to the secondary injury. Our goal was to identify T-cell subpopulations, which trigger the...
4.
Gelderblom M, Arunachalam P, Magnus T
Front Cell Neurosci
. 2014 Nov;
8:368.
PMID: 25414640
Spontaneous or medically induced reperfusion occurs in up to 70% of patients within 24 h after cerebral ischemia. Reperfusion of ischemic brain tissue can augment the inflammatory response that causes...
5.
Gelderblom M, Melzer N, Schattling B, Gob E, Hicking G, Arunachalam P, et al.
Stroke
. 2014 Sep;
45(11):3395-402.
PMID: 25236871
Background And Purpose: Brain injury during stroke results in oxidative stress and the release of factors that include extracellular Ca(2+), hydrogen peroxide, adenosine diphosphate ribose, and nicotinic acid adenine dinucleotide...
6.
Gelderblom M, Daehn T, Schattling B, Ludewig P, Bernreuther C, Arunachalam P, et al.
Neurobiol Dis
. 2013 Aug;
59:177-82.
PMID: 23932916
Objective: We aimed at validating a plasma biomarker for neuronal damage that can be used in acute and chronic models of neurological diseases. Methods: We investigated two different models, middle...
7.
Gelderblom M, Neumann M, Ludewig P, Bernreuther C, Krasemann S, Arunachalam P, et al.
PLoS One
. 2013 May;
8(5):e63118.
PMID: 23658802
The only approved pharmacological treatment for ischemic stroke is intravenous administration of plasminogen activator (tPA) to re-canalize the occluded cerebral vessel. Not only reperfusion but also tPA itself can induce...
8.
Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, et al.
Blood
. 2012 Sep;
120(18):3793-802.
PMID: 22976954
The devastating effect of ischemic stroke is attenuated in mice lacking conventional and unconventional T cells, suggesting that inflammation enhances tissue damage in cerebral ischemia. We explored the functional role...