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Christian Bernreuther

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Articles 143
Citations 2622
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Recent Articles
1.
Viehweger F, Gusinde J, Leege N, Tinger L, Gorbokon N, Menz A, et al.
Hum Pathol . 2025 Mar; 157:105757. PMID: 40054585
Estrogen receptor (ER) is a ligand-activated transcription factor with a critical role in development and function of multiple organ systems and a well-established drug target for breast cancer. To comprehensively...
2.
Caneve P, Schraps N, Moller K, Buyucek S, Lutz F, Chirico V, et al.
Ann Diagn Pathol . 2025 Feb; 76:152448. PMID: 39929118
Brachyury protein plays a role in defining the midline of bilaterian organisms. Commonly expressed in chordomas, brachyury immunohistochemistry is used to distinguish chordomas from their differential diagnoses. However, brachyury expression...
3.
De Wispelaere N, Rico S, Bauer M, Luebke A, Kluth M, Buscheck F, et al.
PLoS One . 2025 Jan; 20(1):e0318271. PMID: 39854331
[This corrects the article DOI: 10.1371/journal.pone.0262877.].
4.
Jansen K, Kornfeld L, Lennartz M, Rico S, Kind S, Reiswich V, et al.
Cancers (Basel) . 2024 Dec; 16(23). PMID: 39682238
Background/objectives: Carcinoembryonic antigen (CEA) is a cell-surface glycoprotein serving as a drug target, diagnostic marker, and serum marker for cancer monitoring. However, prevalence data on CEA expression in cancer tissues...
5.
Buyucek S, Schraps N, Menz A, Lutz F, Chirico V, Viehweger F, et al.
Biomark Res . 2024 Dec; 12(1):154. PMID: 39658782
Background: Claudin-3 (CLDN3) participates in the formation of the tight-junctions (TJs) that regulate intercellular permeability. Altered CLDN3 expression has been linked to tumor progression in multiple tumor types. Despite its...
6.
Lutz F, Hornburg S, Moller K, Viehweger F, Schlichter R, Menz A, et al.
Hum Pathol . 2024 Nov; 154:105695. PMID: 39571690
PAX6 immunohistochemistry (IHC) was proposed as a tool to identify a pancreatic origin of neuroendocrine neoplasms (NENs). To evaluate the diagnostic utility of PAX6 IHC, a tissue microarray containing 19,214...
7.
Schraps N, Port J, Menz A, Viehweger F, Buyucek S, Dum D, et al.
Cancer Med . 2024 Nov; 13(21):e70407. PMID: 39533806
Backround: Anterior gradient 2 (AGR2) is a resident endoplasmic reticulum (ER) protein with a vital role in embryonal development, mucus maturation, tissue regeneration, and wound healing. Methods: To determine the...
8.
Scherzai S, Lennartz M, Jacobsen F, Viehweger F, Dum D, Menz A, et al.
Pathol Res Pract . 2024 Nov; 264:155676. PMID: 39520970
The protein gene product 9.5 (PGP9.5), also termed ubiquitin C-terminal hydrolase L1 (UCH-L1) is an important component of the ubiquitination/deubiquitination system and plays a role in axonal transport. To comprehensively...
9.
Pfefferle S, Schweizer M, Hartmann K, Berger J, Norz D, Emmerich P, et al.
Heliyon . 2024 Oct; 10(19):e38873. PMID: 39444396
Objectives: We report prolonged mpox (>14 weeks) in a patient with HIV complicated by deep tissue MPXV infection despite two courses of tecovirimat treatment. Methods: MPXV-DNA levels in lesional swabs,...
10.
Lutz F, Han S, Buyucek S, Moller K, Viehweger F, Schlichter R, et al.
Diagnostics (Basel) . 2024 Oct; 14(19). PMID: 39410561
Trefoil factor 1 (TFF1) plays a role in the mucus barrier. To evaluate the prevalence of TFF1 expression in cancer, a tissue microarray containing 18,878 samples from 149 tumor types...