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Peter Ludewig

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Articles 39
Citations 845
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Recent Articles
1.
Hagemann N, Qi Y, Mohamud Yusuf A, Li A, Squire A, Tertel T, et al.
Arterioscler Thromb Vasc Biol . 2024 Feb; 44(4):915-929. PMID: 38357819
Background: Until now, the analysis of microvascular networks in the reperfused ischemic brain has been limited due to tissue transparency challenges. Methods: Using light sheet microscopy, we assessed microvascular network...
2.
Gelderblom M, Koch S, Strecker J, Jorgensen C, Garcia-Bonilla L, Ludewig P, et al.
Brain Commun . 2023 Apr; 5(2):fcad090. PMID: 37056478
Multiple consensus statements have called for preclinical randomized controlled trials to improve translation in stroke research. We investigated the efficacy of an interleukin-17A neutralizing antibody in a multi-centre preclinical randomized...
3.
Spangenberg P, Hagemann N, Squire A, Forster N, Krauss S, Qi Y, et al.
Cell Rep Methods . 2023 Apr; 3(3):100436. PMID: 37056368
Light-sheet fluorescence microscopy (LSFM) can produce high-resolution tomograms of tissue vasculature with high accuracy. However, data processing and analysis is laborious due to the size of the datasets. Here, we...
4.
Shang C, Feng K, Hughes E, Clark A, Debnath M, Koscica R, et al.
Light Sci Appl . 2022 Oct; 11(1):299. PMID: 36229447
Monolithic integration of quantum dot (QD) gain materials onto Si photonic platforms via direct epitaxial growth is a promising solution for on-chip light sources. Recent developments have demonstrated superior device...
5.
Wilmes M, Pinto Espinoza C, Ludewig P, Stabernack J, Liesz A, Nicke A, et al.
J Neuroinflammation . 2022 Oct; 19(1):256. PMID: 36224611
Background: Previous studies have demonstrated that purinergic receptors could be therapeutic targets to modulate the inflammatory response in multiple models of brain diseases. However, tools for the selective and efficient...
6.
Mohamud Yusuf A, Hagemann N, Ludewig P, Gunzer M, Hermann D
Front Immunol . 2022 Jan; 12:825572. PMID: 35087539
Following ischemic stroke, polymorphonuclear neutrophils (PMNs) are rapidly recruited to the ischemic brain tissue and exacerbate stroke injury by release of reactive oxygen species (ROS), proteases and proinflammatory cytokines. PMNs...
7.
Baranowsky A, Jahn D, Jiang S, Yorgan T, Ludewig P, Appelt J, et al.
Bone Res . 2022 Jan; 10(1):9. PMID: 35087025
Intermittent injections of parathyroid hormone (iPTH) are applied clinically to stimulate bone formation by osteoblasts, although continuous elevation of parathyroid hormone (PTH) primarily results in increased bone resorption. Here, we...
8.
Piepke M, Clausen B, Ludewig P, Vienhues J, Bedke T, Javidi E, et al.
J Neuroinflammation . 2021 Nov; 18(1):265. PMID: 34772416
Background: Lymphocytes have dichotomous functions in ischemic stroke. Regulatory T cells are protective, while IL-17A from innate lymphocytes promotes the infarct growth. With recent advances of T cell-subtype specific transgenic...
9.
Ludewig P, Graeser M, Forkert N, Thieben F, Randez-Garbayo J, Rieckhoff J, et al.
Wiley Interdiscip Rev Nanomed Nanobiotechnol . 2021 Oct; 14(1):e1757. PMID: 34617413
Stroke is one of the leading worldwide causes of death and sustained disability. Rapid and accurate assessment of cerebral perfusion is essential to diagnose and successfully treat stroke patients. Magnetic...
10.
Boltze J, Aronowski J, Badaut J, Buckwalter M, Caleo M, Chopp M, et al.
Front Aging Neurosci . 2021 Feb; 13:623751. PMID: 33584250
The past decade has brought tremendous progress in diagnostic and therapeutic options for cerebrovascular diseases as exemplified by the advent of thrombectomy in ischemic stroke, benefitting a steeply increasing number...