Matthew Kofron
Overview
Explore the profile of Matthew Kofron including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
503
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Recent Articles
1.
Toth A, Kannan P, Snowball J, Kofron M, Wayman J, Bridges J, et al.
Nat Commun
. 2023 Dec;
14(1):8452.
PMID: 38114516
Lung epithelial regeneration after acute injury requires coordination cellular coordination to pattern the morphologically complex alveolar gas exchange surface. During adult lung regeneration, Wnt-responsive alveolar epithelial progenitor (AEP) cells, a...
2.
Bedard M, Chihanga T, Carlile A, Jackson R, Brusadelli M, Lee D, et al.
Nat Commun
. 2023 Apr;
14(1):1975.
PMID: 37031202
Persistent HPV16 infection is a major cause of the global cancer burden. The viral life cycle is dependent on the differentiation program of stratified squamous epithelium, but the landscape of...
3.
Sur Chowdhury C, Wareham E, Xu J, Kumar S, Kofron M, Lakshmikanthan S, et al.
Front Immunol
. 2022 Dec;
13:1061544.
PMID: 36505495
Introduction: Neutrophils are critical for host immune defense; yet, aberrant neutrophil tissue infiltration triggers tissue damage. Neutrophils are heterogeneous functionally, and adopt 'normal' or 'pathogenic' effector function responses. Understanding neutrophil...
4.
Bedard M, Brusadelli M, Carlile A, Ruiz-Torres S, Lodin H, Lee D, et al.
Viruses
. 2021 Jan;
13(1).
PMID: 33418959
Juvenile-onset recurrent respiratory papillomatosis (JoRRP) is driven by human papillomavirus (HPV) low-risk strains and is associated with significant morbidity. While previous studies of 2D cultures have shed light on disease...
5.
Sharma A, Verma A, Kofron M, Kudira R, Miethke A, Wu T, et al.
Hepatology
. 2020 Feb;
72(5):1800-1818.
PMID: 32064648
Background And Aims: During liver injury, quiescent hepatic stellate cells (qHSCs) transdifferentiate into proliferative and fibrogenic activated myofibroblastic phenotype (activated hepatic stellate cell; aHSCs) expressing smooth muscle α-actin (αSMA) and...
6.
Hinge A, He J, Bartram J, Javier J, Xu J, Fjellman E, et al.
Cell Stem Cell
. 2020 Feb;
26(3):420-430.e6.
PMID: 32059807
The metabolic requirements of hematopoietic stem cells (HSCs) change with their cell cycle activity. However, the underlying role of mitochondria remains ill-defined. Here we found that, after mitochondrial activation with...
7.
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al.
Nat Cell Biol
. 2018 Sep;
20(11):1328.
PMID: 30190576
In the version of this Article originally published, in ref. 34 the first author's name was spelled incorrectly. The correct reference is: Rodón, L. et al. Active CREB1 promotes a...
8.
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al.
Nat Cell Biol
. 2018 Aug;
20(10):1228.
PMID: 30089841
In the version of this Article originally published, the competing interests statement was missing. The authors declare no competing interests; this statement has now been added in all online versions...
9.
Muntifering M, Castranova D, Gibson G, Meyer E, Kofron M, Watson A
Curr Protoc Cytom
. 2018 Jul;
86(1):e38.
PMID: 30005145
Biologic tissues are generally opaque due to optical properties that result in scattering and absorption of light. Preparation of tissues for optical microscopy often involves sectioning to a thickness of...
10.
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al.
Nat Cell Biol
. 2018 Jun;
20(7):823-835.
PMID: 29915361
Stress is integral to tumour evolution, and cancer cell survival depends on stress management. We found that cancer-associated stress chronically activates the bioenergetic sensor AMP kinase (AMPK) and, to survive,...