Prathibha R Gajjala
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Explore the profile of Prathibha R Gajjala including associated specialties, affiliations and a list of published articles.
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13
Citations
156
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Recent Articles
1.
Wen C, Gajjala P, Liu Y, Chen B, Bal M, Sutaria P, et al.
Eur J Med Chem
. 2024 Nov;
281:117016.
PMID: 39520729
Pseudokinase TRIB2, a member of the CAMK Ser/Thr protein kinase family, regulates various cellular processes through phosphorylation-independent mechanisms. Dysregulation of TRIB2 has been implicated in promoting tumor growth, metastasis, and...
2.
Parolia A, Eyunni S, Verma B, Young E, Liu Y, Liu L, et al.
Nat Genet
. 2024 Sep;
56(10):2132-2143.
PMID: 39251788
Androgen receptor (AR) is a ligand-responsive transcription factor that drives terminal differentiation of the prostatic luminal epithelia. By contrast, in tumors originating from these cells, AR chromatin occupancy is extensively...
3.
Parolia A, Eyunni S, Verma B, Young E, Liu L, George J, et al.
bioRxiv
. 2024 Mar;
PMID: 38464251
The androgen receptor (AR) is a ligand-responsive transcription factor that binds at enhancers to drive terminal differentiation of the prostatic luminal epithelia. By contrast, in tumors originating from these cells,...
4.
Gajjala P, Singh P, Odayar V, Ediga H, McCormack F, Madala S
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36769178
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease that is often fatal due to the formation of irreversible scar tissue in the distal areas of the lung. Although...
5.
Gajjala P, Kasam R, Soundararajan D, Sinner D, Huang S, Jegga A, et al.
JCI Insight
. 2021 Sep;
6(20).
PMID: 34520400
Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease associated with unremitting fibroblast activation including fibroblast-to-myofibroblast transformation (FMT), migration, resistance to apoptotic clearance, and excessive deposition of extracellular matrix...
6.
Gajjala P, Madala S
Am J Respir Cell Mol Biol
. 2021 Feb;
64(4):403-404.
PMID: 33591242
No abstract available.
7.
Kasam R, Gajjala P, Jegga A, Courtney J, Randell S, Kramer E, et al.
J Cyst Fibros
. 2020 Jun;
19(5):815-822.
PMID: 32593509
Background: Cystic fibrosis (CF) patients develop severe lung disease including chronic airway infections, neutrophilic inflammation, and progressive fibrotic remodeling in airways. However, cellular and molecular processes that regulate excessive collagen...
8.
Gajjala P, Bruck H, Noels H, Heinze G, Ceccarelli F, Kribben A, et al.
J Mol Med (Berl)
. 2019 Aug;
97(10):1451-1463.
PMID: 31385015
Chronic kidney disease (CKD) may progress to end-stage renal disease (ESRD) at different pace. Early markers of disease progression could facilitate and improve patient management. However, conventional blood and urine...
9.
Sontake V, Gajjala P, Kasam R, Madala S
Expert Opin Ther Targets
. 2018 Nov;
23(1):69-81.
PMID: 30468628
Fibrosis is an irreversible pathological endpoint in many chronic diseases, including pulmonary fibrosis. Idiopathic pulmonary fibrosis (IPF) is a progressive and often fatal condition characterized by (myo)fibroblast proliferation and transformation...
10.
Jansen J, Jankowski J, Gajjala P, Wetzels J, Masereeuw R
Clin Sci (Lond)
. 2017 Jul;
131(14):1631-1647.
PMID: 28667064
In patients with chronic kidney disease (CKD), adequate renal clearance is compromised, resulting in the accumulation of a plethora of uremic solutes. These uremic retention solutes, also named uremic toxins,...