Prashant S Deore
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Explore the profile of Prashant S Deore including associated specialties, affiliations and a list of published articles.
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11
Citations
35
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Recent Articles
1.
Gray M, Deore P, Chung A, Van Riesen A, Manderville R, Seelam Prabhakar P, et al.
Bioconjug Chem
. 2020 Nov;
31(11):2596-2606.
PMID: 33156614
Fluorescent nucleobases represent an important class of molecular reporters of nucleic acid interactions. In this work, the advantages of utilizing a noncanonical fluorescent nucleobase surrogate for monitoring thrombin binding by...
2.
Armstrong-Price D, Deore P, Manderville R
J Agric Food Chem
. 2020 Jan;
68(7):2249-2255.
PMID: 31986034
Ochratoxin A (OTA) is an intrinsically fluorescent phenolic mycotoxin that contaminates a wide range of food products and is a serious health threat to animals and humans. An OTA binding...
3.
Deore P, Manderville R
Analyst
. 2020 Jan;
145(4):1288-1293.
PMID: 31895357
Fluorescent ligands that selectively bind to a specific G-quadruplex (GQ) topology (antiparallel, hybrid or parallel) are highly sought after for aptasensor development and nanodevice construction. The coumarin-benzothiazole hybrid (BnBtC) is...
4.
Deore P, Gray M, Chung A, Manderville R
J Am Chem Soc
. 2019 Aug;
141(36):14288-14297.
PMID: 31436972
G-Quadruplexes (GQs) serve as popular recognition elements for DNA aptasensors and are incorporated into a DNA nanodevice capable of controlled conformational changes to activate a sensing mechanism. Herein we highlight...
5.
Deore P, Coman D, Manderville R
Chem Commun (Camb)
. 2019 Mar;
55(24):3540-3543.
PMID: 30839953
The coumarin-hemicyanine hybrid is an internal charge transfer (ICT) dye that features a donor-π-acceptor motif and displays two well-resolved absorption bands at ∼350 nm for the donor coumarin and ∼550...
6.
Chung A, Deore P, Al-Abdul-Wahid S, Aboelnga M, Wetmore S, Manderville R
J Org Chem
. 2019 Jan;
84(4):2261-2268.
PMID: 30664354
Promoting selective interactions between a nucleophile and electrophilic dye in complex environments is a central goal in nucleophilic chemosensor development. Commonly employed dyes are hemicyanines containing either the N-methylbenzothiazolium (Btz)...
7.
Deore P, Soldatov D, Manderville R
Sci Rep
. 2018 Nov;
8(1):16874.
PMID: 30442930
Fluorescent probes that can distinguish different DNA topologies through changes in optical readout are sought after for DNA-based diagnostics. In this work, the 4,4-difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) chromophore attached to cyanophenyl...
8.
Van Riesen A, Fadock K, Deore P, Desoky A, Manderville R, Sowlati-Hashjin S, et al.
Org Biomol Chem
. 2018 May;
16(20):3831-3840.
PMID: 29745412
Chemically modified aptamers have the opportunity to increase aptamer target binding affinity and provide structure-activity relationships to enhance our understanding of molecular target recognition by the aptamer fold. In the...
9.
Deore P, Argade N
J Org Chem
. 2014 Mar;
79(6):2538-46.
PMID: 24593305
With dimethyl maleate as the starting material, facile stereoselective syntheses of natural and unnatural conjugated alkenyl(methyl)maleic anhydrides have been described. The key reactions were base-endorsed novel 1,2-, 1,4-, and 1,6-eliminations...
10.
Deore P, Argade N
Org Lett
. 2013 Nov;
15(22):5826-9.
PMID: 24175675
Remarkable reactivity reversal stratagem in 3,4-disubstituted butenolides under acidic conditions is described. Design of a suitably substituted multifunctional butenolide followed by an acid-catalyzed chemo- and diastereoselective intramolecular ring closure via...