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Pranav Joshi

Explore the profile of Pranav Joshi including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 136
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Recent Articles
1.
Narendra A, Seibel A, Ramirez-Esquivel F, Joshi P, McLean D, Robledo-Ospina L, et al.
J Exp Biol . 2025 Feb; 228(3). PMID: 39936309
Jumping requires a rapid release of energy to propel an animal. Terrestrial animals achieve this by relying on the power generated by muscles, or by storing and rapidly releasing elastic...
2.
Joshi P, Acharya P, Zolfaghar M, Vanga M, Shrestha S, Lee M
Methods Mol Biol . 2025 Jan; PMID: 39821810
Human brain organoids (HBOs) derived from pluripotent stem cells hold great potential for disease modeling and high-throughput compound screening, given their structural and functional resemblance to fetal brain tissues. These...
3.
Joshi P, Nascimento H, Kang S, Lee M, Vanga M, Lee S, et al.
Biotechnol Bioeng . 2025 Jan; 122(4):995-1009. PMID: 39821523
Recent advancements in three-dimensional (3D) cell culture technologies, such as cell spheroids, organoids, and 3D bioprinted tissue constructs, have significantly improved the physiological relevance of in vitro models. These models...
4.
Zolfaghar M, Acharya P, Joshi P, Choi N, Shrestha S, Lekkala V, et al.
ACS Biomater Sci Eng . 2024 Oct; 10(11):7111-7119. PMID: 39454131
Cryopreservation in cryovials extends cell storage at low temperatures, and advances in organoid cryopreservation improve reproducibility and reduce generation time. However, cryopreserving human organoids presents challenges due to the limited...
5.
Acharya P, Shrestha S, Joshi P, Choi N, Lekkala V, Kang S, et al.
Biofabrication . 2024 Oct; 17(1). PMID: 39444222
Despite the potential toxicity of commercial chemicals to the development of the nervous system (known as developmental neurotoxicity or DNT), conventionalcell models have primarily been employed for the assessment of...
6.
Joshi P, Kang S, Acharya P, Vanga M, Lee M
Curr Protoc . 2024 Oct; 4(10):e70023. PMID: 39373184
The liver's role in the biotransformation of chemicals is critical for both augmented toxicity and detoxification. However, there has been a significant lack of effort to integrate biotransformation into in...
7.
Zolfaghar M, Acharya P, Joshi P, Choi N, Shrestha S, Lekkala V, et al.
bioRxiv . 2024 Aug; PMID: 39091876
Cryopreservation in cryovials extends cell storage at low temperatures, and advances in organoid cryopreservation improve reproducibility and reduce generation time. However, cryopreserving human organoids presents challenges due to the limited...
8.
Lekkala V, Kang S, Liu J, Shrestha S, Acharya P, Joshi P, et al.
ACS Biomater Sci Eng . 2024 May; 10(5):3478-3488. PMID: 38695610
Static three-dimensional (3D) cell culture has been demonstrated in ultralow attachment well plates, hanging droplet plates, and microtiter well plates with hydrogels or magnetic nanoparticles. Although it is simple, reproducible,...
9.
Shrestha S, Acharya P, Kang S, Vanga M, Lekkala V, Liu J, et al.
bioRxiv . 2024 Apr; PMID: 38586058
Human liver organoids (HLOs) differentiated from embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and adult stem cells (ASCs) can recapitulate the structure and function of human fetal liver...
10.
Acharya P, Shrestha S, Joshi P, Choi N, Lekkala V, Kang S, et al.
bioRxiv . 2024 Apr; PMID: 38559002
Despite the potential toxicity of commercial chemicals to the development of the nervous system (known as developmental neurotoxicity or DNT), conventional cell models have primarily been employed for the assessment...