Kyeong-Nam Yu
Overview
Explore the profile of Kyeong-Nam Yu including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
571
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Recent Articles
1.
Bigdelou P, Chan K, Tang J, Yu K, Whited J, Wang D, et al.
Exp Cell Res
. 2020 Aug;
396(1):112243.
PMID: 32835658
It is challenging to rapidly identify immune responses that reflect the state and capability of immune cells due to complex heterogeneity of immune cells and their plasticity to pathogens and...
2.
Joshi P, Kang S, Yu K, Kothapalli C, Lee M
Toxicol In Vitro
. 2020 Jan;
65:104765.
PMID: 31923580
The assessment of neurotoxicity has been performed traditionally with animals. However, in vivo studies are highly expensive and time-consuming, and often do not correlate to human outcomes. Thus, there is...
3.
Kang S, Yu K, Joshi P, Lee M
Methods Mol Biol
. 2019 Nov;
2089:191-207.
PMID: 31773656
A variety of oxidative and conjugative enzymes are involved in the metabolism of compounds including drugs, which can be converted into toxic metabolites by Phase I drug-metabolizing enzymes (DMEs), such...
4.
Joshi P, Yu K, Kang S, Kwon S, Kwon P, Dordick J, et al.
Exp Cell Res
. 2018 Jul;
370(2):680-691.
PMID: 30048616
Numerous chemicals including environmental toxicants and drugs have not been fully evaluated for developmental neurotoxicity. A key gap exists in the ability to predict accurately and robustly in vivo outcomes...
5.
Yu K, Kang S, Hong S, Lee M
Arch Toxicol
. 2018 Jul;
92(8):2501-2516.
PMID: 29974144
The US Environmental Protection Agency (EPA) launched the Transform Tox Testing Challenge in 2016 with the goal of developing practical methods that can be integrated into conventional high-throughput screening (HTS)...
6.
Joshi P, Datar A, Yu K, Kang S, Lee M
Toxicol In Vitro
. 2018 Mar;
50:147-159.
PMID: 29501531
The majority of high-content imaging (HCI) assays have been performed on two-dimensional (2D) cell monolayers for its convenience and throughput. However, 2D-cultured cell models often do not represent the in...
7.
Yu S, Joshi P, Park Y, Yu K, Lee M
Biotechnol Prog
. 2017 Dec;
34(2):445-454.
PMID: 29240313
Layer-by-layer cell printing is useful in mimicking layered tissue structures inside the human body and has great potential for being a promising tool in the field of tissue engineering, regenerative...
8.
Yu K, Nadanaciva S, Rana P, Lee D, Ku B, Roth A, et al.
Arch Toxicol
. 2017 Nov;
92(3):1295-1310.
PMID: 29167929
Human liver contains various oxidative and conjugative enzymes that can convert nontoxic parent compounds to toxic metabolites or, conversely, toxic parent compounds to nontoxic metabolites. Unlike primary hepatocytes, which contain...
9.
Yu K, Kim H, Kim S, Dawaadamdin O, Lee A, Hong S, et al.
Nicotine Tob Res
. 2016 Sep;
18(9):1877-1885.
PMID: 27611309
Introduction: Cigarette smoke (CS) is associated with a broad range of diseases including lung cancer. Many researchers have suggested that cigarette smoke condensate (CSC) may be more toxic compared to...
10.
Hong S, Chang S, Cho K, Kim S, Park S, Lee A, et al.
Oncotarget
. 2016 Sep;
7(40):65335-65347.
PMID: 27588471
Trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus is elevated in cancer cells. Therefore, proteins of the ER-Golgi intermediate compartment (ERGIC) attract significant attention as targets for cancer...