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Pragya Mittal

Explore the profile of Pragya Mittal including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 72
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Recent Articles
1.
Mittal P, Sinha A, Pandiyan A, Kumari L, Ray M, Pavankumar T
J Biol Chem . 2024 Jul; 300(8):107600. PMID: 39059490
RNase R (encoded by the rnr gene) is a highly processive 3' → 5' exoribonuclease essential for the growth of the psychrotrophic bacterium Pseudomonas syringae Lz4W at low temperature. The...
2.
Mittal P, Sipani R, Pandiyan A, Sulthana S, Sinha A, Hussain A, et al.
Appl Environ Microbiol . 2023 Oct; 89(11):e0116823. PMID: 37905926
Bacterial exoribonucleases play a crucial role in RNA maturation, degradation, quality control, and turnover. In this study, we have uncovered a previously unknown role of 3'-5' exoribonuclease RNase R of...
3.
Roy S, Mittal P, Tayi L, Bondada S, Ray M, Patel H, et al.
Phytopathology . 2021 Aug; 112(3):501-510. PMID: 34384245
Exoribonuclease R (RNase R) is a 3' hydrolytic exoribonuclease that can degrade structured RNA. Mutation in RNase R affects virulence of certain human pathogenic bacteria. The aim of this study...
4.
Pavankumar T, Mittal P, Hallsworth J
Environ Microbiol . 2020 Nov; 23(7):3665-3681. PMID: 33169927
Low temperatures constrain cellular life due to reductions in nutrient uptake, enzyme kinetics, membrane permeability, and function of other biomacromolecules. This has implications for the biophysical limits of life on...
5.
Mittal P, Brindle J, Stephen J, Plotkin J, Kudla G
Proc Natl Acad Sci U S A . 2018 Aug; 115(34):8639-8644. PMID: 30082392
Many organisms are subject to selective pressure that gives rise to unequal usage of synonymous codons, known as codon bias. To experimentally dissect the mechanisms of selection on synonymous sites,...
6.
Sinha A, Pavankumar T, Kamisetty S, Mittal P, Ray M
Mol Microbiol . 2013 Jul; 89(4):792-810. PMID: 23815755
Chromosomal damage was detected previously in the recBCD mutants of the Antarctic bacterium Pseudomonas syringae Lz4W, which accumulated linear chromosomal DNA leading to cell death and growth inhibition at 4°C....
7.
Sulthana S, Rajyaguru P, Mittal P, Ray M
Appl Environ Microbiol . 2011 Sep; 77(22):7896-904. PMID: 21926201
RNase R is a highly processive, hydrolytic 3'-5' exoribonuclease belonging to the RNB/RNR superfamily which plays significant roles in RNA metabolism in bacteria. The enzyme was observed to be essential...