Poonam Dhindwal
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Explore the profile of Poonam Dhindwal including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
13
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Recent Articles
1.
Asar R, Dhindwal P, Ruzzini A
J Biol Chem
. 2024 Sep;
300(10):107769.
PMID: 39276930
The bile salt hydrolases (BSHs) are significant constituents of animal microbiomes. An evolving appreciation of their roles in health and disease has established them as targets of pharmacological inhibition. These...
2.
Dhindwal P, Boniecki M, Moore S
Protein Sci
. 2023 Dec;
33(2):e4882.
PMID: 38151822
In bacterial flagellum biogenesis, secretion of the hook-filament junction proteins FlgK and FlgL and completion of the flagellum requires the FlgN chaperone. Similarly, the related FliT chaperone is necessary for...
3.
Dhindwal P, Myziuk I, Ruzzini A
Trends Microbiol
. 2023 Sep;
31(12):1199-1201.
PMID: 37689489
Antibiotics often contain ester bonds. The macrocyclic lactones of macrolides are pre-eminent examples in which ester bonds are essential to the form and function of antibiotics. Bacterial macrolide esterases that...
4.
Dhindwal P, Thompson C, Kos D, Planedin K, Jain R, Jelinski M, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(8):e2219827120.
PMID: 36791107
The discovery of unreported antimicrobial resistance genes (ARGs) remains essential. Here, we report the identification and preliminary characterization of an α/β-hydrolase that inactivates macrolides. This serine-dependent macrolide esterase co-occurs with...