» Authors » Polly E Mattila

Polly E Mattila

Explore the profile of Polly E Mattila including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 12
Citations 239
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Yeo R, Mau T, Ross Z, Edenhoffer N, Liu J, Barnes H, et al.
J Gerontol A Biol Sci Med Sci . 2025 Jan; PMID: 39886989
Background: Age-related changes in adipose tissue impact chronic medical diseases and mobility disability but mechanism remains poorly understood. The goal of this study is to define methods for phenotyping unique...
2.
Kanshana J, Mattila P, Ewing M, Wood A, Schoiswohl G, Meyer A, et al.
PLoS One . 2021 Sep; 16(9):e0251895. PMID: 34520472
Obesity and diabetes have strong heritable components, yet the genetic contributions to these diseases remain largely unexplained. In humans, a missense variant in Creb3 regulatory factor (CREBRF) [rs373863828 (p.Arg457Gln); CREBRFR457Q]...
3.
Frahm K, Williams A, Wood A, Ewing M, Mattila P, Chuan B, et al.
Endocrinology . 2020 Sep; 161(11). PMID: 32901804
Glucocorticoid signaling controls many key biological functions ranging from stress responses to affective states. The putative transcriptional coregulator CREB3 regulatory factor (CREBRF) reduces glucocorticoid receptor levels in vitro, suggesting that...
4.
Mattila P, Raghavan V, Rbaibi Y, Baty C, Weisz O
Am J Physiol Cell Physiol . 2013 Oct; 306(5):C441-9. PMID: 24153428
The proximal tubule (PT) reabsorbs the majority of sodium, bicarbonate, and chloride ions, phosphate, glucose, water, and plasma proteins from the glomerular filtrate. Despite the critical importance of endocytosis for...
5.
Mattila P, Youker R, Mo D, Bruns J, Cresawn K, Hughey R, et al.
Traffic . 2011 Nov; 13(3):433-42. PMID: 22118573
Many newly synthesized membrane proteins traverse endocytic intermediates en route to the surface in polarized epithelial cells; however, the biosynthetic itinerary of secreted proteins has not been elucidated. We monitored...
6.
Kinlough C, Poland P, Gendler S, Mattila P, Mo D, Weisz O, et al.
J Biol Chem . 2011 Sep; 286(45):39072-81. PMID: 21937430
MUC1 is efficiently delivered to the apical surface of polarized Madin-Darby canine kidney (MDCK) cells by transit through apical recycling endosomes, a route associated with delivery of apical proteins with...
7.
Folsch H, Mattila P, Weisz O
Traffic . 2009 May; 10(8):972-81. PMID: 19453969
The maintenance of epithelial cell function requires the establishment and continuous renewal of differentiated apical and basolateral plasma membrane domains with distinct lipid and protein compositions. Newly synthesized proteins destined...
8.
Mattila P, Kinlough C, Bruns J, Weisz O, Hughey R
Biol Chem . 2009 May; 390(7):551-6. PMID: 19453277
MUC1 is a heavily glycosylated transmembrane protein localized at the apical surface of polarized epithelial cells. Here, we examined the biosynthetic route of newly synthesized MUC1 in polarized Madin-Darby canine...
9.
Mattila P, Metz A, Rapaka R, Bauer L, Steele C
Antimicrob Agents Chemother . 2007 Dec; 52(3):1171-2. PMID: 18086835
Invasive pulmonary aspergillosis (IPA) has significantly increased over the last decade. Here, a fusion protein consisting of the Dectin-1 extracellular domain linked to the Fc portion of murine immunoglobulin G1...
10.
Schaff U, Mattila P, Simon S, Walcheck B
J Leukoc Biol . 2007 Oct; 83(1):99-105. PMID: 17928459
E-selectin is expressed by the vascular endothelium and binds flowing neutrophils in the blood to facilitate their recruitment into the underlying tissue at sites of inflammation. L-selectin on neutrophils is...