Po-Chien Lu
Overview
Explore the profile of Po-Chien Lu including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
60
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0
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Recent Articles
1.
Chang T, Hsu K, Luo C, Yen J, Lu P, Chang C
Interact Cardiovasc Thorac Surg
. 2020 Jan;
30(3):408-416.
PMID: 31899505
Objectives: Handmade trileaflet expanded polytetrafluoroethylene valved conduit developed using the flip-over method has been tailored for pulmonary valve reconstruction with satisfactory outcomes. We investigated the in vitro performance of the...
2.
Yen J, Chen S, Chern M, Lu P
J Artif Organs
. 2014 Mar;
17(2):178-85.
PMID: 24619800
Non-physiologic turbulent flow occurs in medical cardiovascular devices resulting in hemodynamic stresses that may damage red blood cells (RBC) and cause hemolysis. Hemolysis was previously thought to result from Reynolds...
3.
Li C, Lu P
J Artif Organs
. 2012 Jun;
15(4):364-74.
PMID: 22692363
The closing velocity of the leaflets of mechanical heart valves is excessively rapid and can cause the cavitation phenomenon. Cavitation bubbles collapse and produce high pressure which then damages red...
4.
Li C, Chen S, Lo C, Lu P
J Artif Organs
. 2011 Oct;
15(1):57-64.
PMID: 22015913
Bubble cavitation occurs in the flow field when local pressure drops below vapor pressure. One hypothesis states that low-pressure regions in vortices created by instantaneous valve closure and occluder rebound...
5.
Li C, Chen S, Lo C, Lu P
ASAIO J
. 2011 Apr;
57(3):188-96.
PMID: 21499078
Design limitations of current mechanical heart valves cause blood flow to separate at the leaflet edges and annular valve base, forming downstream vortex mixing and high turbulent shear stresses. The...
6.
Lo C, Chen S, Li C, Lu P
Ann Biomed Eng
. 2010 May;
38(10):3162-72.
PMID: 20490686
When studying mechanical heart valve cavitation, a physical model allows direct flow field and pressure measurements that are difficult to perform with actual valves, as well as separate testing of...
7.
Li C, Lo C, Lu P
Ann Biomed Eng
. 2009 Dec;
38(3):903-16.
PMID: 20020213
Among the clinical complications of mechanical heart valves (MHVs), hemolysis was previously thought to result from Reynolds stresses in turbulent flows. A more recent hypothesis suggests viscous dissipative stresses at...
8.
Li C, Lu P, Liu J, Lo C, Hwang N
J Heart Valve Dis
. 2008 Aug;
17(4):435-45.
PMID: 18751474
Background And Aim Of The Study: Cavitation occurs during mechanical heart valve closure when the local pressure drops below vapor pressure. The formation of stable gas bubbles may result in...
9.
Lo C, Liu J, Li C, Lu P, Hwang N
ASAIO J
. 2008 Mar;
54(2):163-71.
PMID: 18356649
Accelerated testing provides a substantial amount of data on mechanical heart valve durability in a short period of time, but such conditions may not accurately reflect in vivo performance. Cavitation,...
10.
Lo C, Lu P, Liu J, Li C, Hwang N
ASAIO J
. 2008 Mar;
54(2):156-62.
PMID: 18356648
High-speed squeeze flow during mechanical valve closure is often thought to cause cavitation, either between the leaflet tip and flat contact area in the valve housing, seating lip, or strut...