Piotr Bragoszewski
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Explore the profile of Piotr Bragoszewski including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Bragoszewski P, Wasilewski M, Sakowska P, Gornicka A, Bottinger L, Qiu J, et al.
Proc Natl Acad Sci U S A
. 2015 Jun;
112(25):7713-8.
PMID: 26056291
The content of mitochondrial proteome is maintained through two highly dynamic processes, the influx of newly synthesized proteins from the cytosol and the protein degradation. Mitochondrial proteins are targeted to...
12.
Gornicka A, Bragoszewski P, Chroscicki P, Wenz L, Schulz C, Rehling P, et al.
Mol Biol Cell
. 2014 Oct;
25(25):3999-4009.
PMID: 25318675
Mitochondrial proteins are synthesized on cytosolic ribosomes and imported into mitochondria with the help of protein translocases. For the majority of precursor proteins, the role of the translocase of the...
13.
Bragoszewski P, Gornicka A, Sztolsztener M, Chacinska A
Mol Cell Biol
. 2013 Mar;
33(11):2136-48.
PMID: 23508107
Mitochondrial precursor proteins are synthesized in the cytosol and subsequently imported into mitochondria. The import of mitochondrial intermembrane space proteins is coupled with their oxidative folding and governed by the...
14.
Bottinger L, Gornicka A, Czerwik T, Bragoszewski P, Loniewska-Lwowska A, Schulze-Specking A, et al.
Mol Biol Cell
. 2012 Aug;
23(20):3957-69.
PMID: 22918950
The intermembrane space of mitochondria accommodates the essential mitochondrial intermembrane space assembly (MIA) machinery that catalyzes oxidative folding of proteins. The disulfide bond formation pathway is based on a relay...
15.
Stojanovski D, Bragoszewski P, Chacinska A
Biochim Biophys Acta
. 2012 May;
1823(7):1142-50.
PMID: 22579494
Many newly synthesized proteins obtain disulfide bonds in the bacterial periplasm, the endoplasmic reticulum (ER) and the mitochondrial intermembrane space. The acquisition of disulfide bonds is critical for the folding,...
16.
Milczarski P, Bolibok-Bragoszewska H, Myskow B, Stojalowski S, Heller-Uszynska K, Goralska M, et al.
PLoS One
. 2011 Dec;
6(12):e28495.
PMID: 22163026
Background: Rye (Secale cereale L.) is an economically important crop, exhibiting unique features such as outstanding resistance to biotic and abiotic stresses and high nutrient use efficiency. This species presents...
17.
Mikula M, Gaj P, Dzwonek K, Rubel T, Karczmarski J, Paziewska A, et al.
DNA Res
. 2010 Jul;
17(4):245-60.
PMID: 20587588
Definitive identification of promoters, their cis-regulatory motifs, and their trans-acting proteins requires experimental analysis. To define the HNRNPK promoter and its cognate DNA-protein interactions, we performed a comprehensive study combining...
18.
Bragoszewski P, Kupryjanczyk J, Bartnik E, Rachinger A, Ostrowski J
BMC Cancer
. 2008 Oct;
8:292.
PMID: 18842121
Background: In recent years, numerous studies have investigated somatic mutations in mitochondrial DNA in various tumours. The observed high mutation rates might reflect mitochondrial deregulation; consequently, mutation analyses could be...
19.
Bragoszewski P, Habior A, Walewska-Zielecka B, Ostrowski J
Acta Biochim Pol
. 2007 May;
54(2):341-8.
PMID: 17502923
In patients without substantial alcohol use, triglyceride accumulation in the liver can lead to nonalcoholic fatty liver disease (NAFLD) that may progress to nonalcoholic steatohepatitis (NASH). The differential diagnosis between...
20.
Ostrowski J, Mikula M, Karczmarski J, Rubel T, Wyrwicz L, Bragoszewski P, et al.
J Mol Med (Berl)
. 2007 Apr;
85(7):733-43.
PMID: 17415542
Barrett's esophagus is characterized by the replacement of squamous epithelium with specialized intestinal metaplastic mucosa. The exact mechanisms of initiation and development of Barrett's metaplasia remain unknown, but a hypothesis...