Peter Rehling
Overview
Explore the profile of Peter Rehling including associated specialties, affiliations and a list of published articles.
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Articles
147
Citations
5525
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Recent Articles
1.
Yousefi R, Cruz-Zaragoza L, Valpadashi A, Hansohn C, Dahal D, Richter-Dennerlein R, et al.
Cell Rep
. 2025 Feb;
44(1):115143.
PMID: 39932185
Mitochondrial DNA encodes 13 subunits of the oxidative phosphorylation (OXPHOS) system, which are synthesized inside the organelle and essential for cellular energy supply. How mitochondrial gene expression is regulated and...
2.
Oborska-Oplova M, Geiger A, Michel E, Klingauf-Nerurkar P, Dennerlein S, Bykov Y, et al.
Nat Cell Biol
. 2025 Jan;
27(2):336-346.
PMID: 39890954
The correct sorting of nascent ribosomal proteins from the cytoplasm to the nucleus or to mitochondria for ribosome production poses a logistical challenge for cellular targeting pathways. Here we report...
3.
Valenti R, David Y, Edilbi D, Dubreuil B, Boshnakovska A, Asraf Y, et al.
J Cell Biol
. 2024 Dec;
224(2).
PMID: 39692734
Genome-wide collections of yeast strains, known as libraries, revolutionized the way systematic studies are carried out. Specifically, libraries that involve a cellular perturbation, such as the deletion collection, have facilitated...
4.
Shumanska M, Lodygin D, Gibhardt C, Ickes C, Stejerean-Todoran I, Krause L, et al.
EMBO Rep
. 2024 Dec;
26(2):407-442.
PMID: 39623165
T-cell receptor (TCR)-induced Ca signals are essential for T-cell activation and function. In this context, mitochondria play an important role and take up Ca to support elevated bioenergetic demands. However,...
5.
Jain N, Gomkale R, Rehling P
Methods Enzymol
. 2024 Nov;
707:3-22.
PMID: 39488380
Mitochondria import the vast majority of proteins from the cytosol. Protein translocation machineries in outer and inner membranes facilitate precursor recognition and transport. Most mitochondrial proteins utilize N-terminal presequences as...
6.
Foo B, Amedei H, Kaur S, Jaawan S, Boshnakovska A, Gall T, et al.
PLoS One
. 2024 Oct;
19(10):e0311203.
PMID: 39446877
Phospholamban (PLN) is a sarco-endoplasmic reticulum (SER) membrane protein that regulates cardiac contraction/relaxation by reversibly inhibiting the SERCA2a Ca2+-reuptake pump. The R14Δ-PLN mutation causes severe cardiomyopathy that is resistant to...
7.
Reshetniak S, Bogaciu C, Bonn S, Brose N, Cooper B, DEste E, et al.
J Physiol
. 2024 Oct;
PMID: 39367860
The synaptic vesicle cluster (SVC) is an essential component of chemical synapses, which provides neurotransmitter-loaded vesicles during synaptic activity, at the same time as also controlling the local concentrations of...
8.
Aich A, Boshnakovska A, Witte S, Gall T, Unthan-Fechner K, Yousefi R, et al.
Nat Commun
. 2024 Aug;
15(1):6914.
PMID: 39134548
Mitochondrial oxidative phosphorylation (OXPHOS) fuels cellular ATP demands. OXPHOS defects lead to severe human disorders with unexplained tissue specific pathologies. Mitochondrial gene expression is essential for OXPHOS biogenesis since core...
9.
Schneider C, Hilbert J, Genevaux F, Hofer S, Krauss L, Schicktanz F, et al.
Adv Sci (Weinh)
. 2024 Jun;
11(31):e2307695.
PMID: 38885414
Cancer cells must develop strategies to adapt to the dynamically changing stresses caused by intrinsic or extrinsic processes, or therapeutic agents. Metabolic adaptability is crucial to mitigate such challenges. Considering...
10.
Kremer L, Rehling P
Hum Mol Genet
. 2024 May;
33(R1):R47-R52.
PMID: 38779773
The mitochondrial oxidative phosphorylation (OXPHOS) system produces the majority of energy required by cells. Given the mitochondrion's endosymbiotic origin, the OXPHOS machinery is still under dual genetic control where most...