Pietro Mancuso
Overview
Explore the profile of Pietro Mancuso including associated specialties, affiliations and a list of published articles.
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Snapshot
Snapshot
Articles
19
Citations
471
Followers
0
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Recent Articles
1.
Burdo T, Chen C, Kaminski R, Sariyer I, Mancuso P, Donadoni M, et al.
Gene Ther
. 2024 Jan;
31(7-8):434-435.
PMID: 38212405
No abstract available.
2.
Burdo T, Chen C, Kaminski R, Sariyer I, Mancuso P, Donadoni M, et al.
Gene Ther
. 2023 Aug;
31(5-6):224-233.
PMID: 37587230
In this study, we demonstrate the safety and utility of CRISPR-Cas9 gene editing technology for in vivo editing of proviral DNA in ART-treated, virally controlled simian immunodeficiency virus (SIV) infected...
3.
Dash P, Chen C, Kaminski R, Su H, Mancuso P, Sillman B, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(19):e2217887120.
PMID: 37126704
Treatment of HIV-1-infected CD34+ NSG-humanized mice with long-acting ester prodrugs of cabotegravir, lamivudine, and abacavir in combination with native rilpivirine was followed by dual CRISPR-Cas9 C-C chemokine receptor type five...
4.
Tricarico R, Madzo J, Scher G, Cohen M, Jelinek J, Maegawa S, et al.
Gastroenterology
. 2023 Feb;
164(6):921-936.e1.
PMID: 36764492
Background & Aims: Aberrant DNA methylation is frequent in colorectal cancer (CRC), but underlying mechanisms and pathologic consequences are poorly understood. Methods: We disrupted active DNA demethylation genes Tet1 and/or...
5.
Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, et al.
Oncogene
. 2022 May;
41(23):3300-3301.
PMID: 35505094
No abstract available.
6.
Mancuso P, Chen C, Kaminski R, Gordon J, Liao S, Robinson J, et al.
Nat Commun
. 2020 Nov;
11(1):6065.
PMID: 33247091
Elimination of HIV DNA from infected individuals remains a challenge in medicine. Here, we demonstrate that intravenous inoculation of SIV-infected macaques, a well-accepted non-human primate model of HIV infection, with...
7.
Sannai M, Doneddu V, Giri V, Seeholzer S, Nicolas E, Yip S, et al.
DNA Repair (Amst)
. 2019 Sep;
82:102687.
PMID: 31476572
The base excision repair DNA N-glycosylase MBD4 (also known as MED1), an interactor of the DNA mismatch repair protein MLH1, plays a central role in the maintenance of genomic stability...
8.
Dash P, Kaminski R, Bella R, Su H, Mathews S, Ahooyi T, et al.
Nat Commun
. 2019 Jul;
10(1):2753.
PMID: 31266936
Elimination of HIV-1 requires clearance and removal of integrated proviral DNA from infected cells and tissues. Here, sequential long-acting slow-effective release antiviral therapy (LASER ART) and CRISPR-Cas9 demonstrate viral clearance...
9.
Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, et al.
Oncogene
. 2019 Jan;
38(19):3710-3728.
PMID: 30674989
Melanoma is an aggressive neoplasm with increasing incidence that is classified by the NCI as a recalcitrant cancer, i.e., a cancer with poor prognosis, lacking progress in diagnosis and treatment....
10.
Bella R, Kaminski R, Mancuso P, Young W, Chen C, Sariyer R, et al.
Mol Ther Nucleic Acids
. 2018 Sep;
12:275-282.
PMID: 30195766
We used NOD/SCID mice, also known as NRG, to assess the ability of lentivirus-mediated intravenous delivery of CRISPR in editing the HIV-1 genome from the circulating PBMC engrafts, some of...