Pieter A van der Velden
Overview
Explore the profile of Pieter A van der Velden including associated specialties, affiliations and a list of published articles.
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58
Citations
1306
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Recent Articles
1.
Nell R, Versluis M, Cats D, Mei H, Verdijk R, Kroes W, et al.
Sci Rep
. 2025 Mar;
15(1):8167.
PMID: 40059100
Uveal melanoma is a lethal intraocular tumour, in which the presence of various genetic alterations correlates with the risk of metastatic dissemination and survival. Here, we tested the detectability of...
2.
Gelmi M, Gezgin G, van der Velden P, Luyten G, Luk S, Heemskerk M, et al.
Invest Ophthalmol Vis Sci
. 2023 Dec;
64(15):36.
PMID: 38149971
Purpose: Uveal melanoma (UM) is a rare disease with a high mortality, and new therapeutic options are being investigated. Preferentially Expressed Antigen in Melanoma (PRAME) is a cancer testis antigen,...
3.
Gelmi M, Verdijk R, Houtzagers L, van der Velden P, Kroes W, Luyten G, et al.
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37240204
Microphthalmia-associated transcription factor (MITF) is an important regulator of melanogenesis and melanocyte development. In cutaneous melanoma, MITF loss has been linked to an increased expression of stem cell markers, a...
4.
Gezgin G, Visser M, Ruano D, Santegoets S, de Miranda N, van der Velden P, et al.
Ophthalmol Sci
. 2022 Oct;
2(2):100132.
PMID: 36249685
Purpose: To evaluate whether expanded tumor-infiltrating lymphocytes (TILs) can be obtained from primary uveal melanoma (UM) for potential use as adjuvant treatment in patients at risk of developing metastatic disease....
5.
Nell R, Zoutman W, Versluis M, van der Velden P
Methods Mol Biol
. 2022 May;
2453:191-208.
PMID: 35622328
An accurate T cell quantification is prognostically and therapeutically relevant in various clinical applications, including oncology care and research. In this chapter, we describe how T cell quantifications can be...
6.
Piaggio F, Croce M, Reggiani F, Monti P, Bernardi C, Ambrosio M, et al.
Eur J Cancer
. 2022 May;
170:27-41.
PMID: 35580369
Background And Aim Of The Study: Mutations in the Gα-genes GNAQ and GNA11 are found in 85-90% of uveal melanomas (UM). Aim of the study is to understand whether the...
7.
van de Leemkolk F, Nell R, Versluis M, de Koning E, Huurman V, Alwayn I, et al.
Transpl Int
. 2022 Apr;
35:10167.
PMID: 35462792
Assessment of specific β-cell death can be used to determine the quality and viability of pancreatic islets prior to transplantation and hence predict the suitability of the pancreas for isolation....
8.
Zoutman W, Nell R, Versluis M, Pico I, Vu T, Verdijk R, et al.
Mol Immunol
. 2022 Mar;
145:109-123.
PMID: 35339027
B cells fulfill an important role in the adaptive immunity. Upon activation and immunoglobulin (IG) class switching, these cells function in the humoral immunity compartment as plasma cells. For clinical...
9.
de Lange M, Nell R, van der Velden P
Mol Biomed
. 2022 Jan;
2(1):25.
PMID: 35006486
Here, we discuss the presence and roles of heterogeneity in the development of uveal melanoma. Both genetic and cellular heterogeneity are considered, as their presence became undeniable due to single...
10.
Nell R, Zoutman W, Calbet-Llopart N, Garcia A, Menger N, Versluis M, et al.
J Mol Diagn
. 2021 Nov;
24(1):88-100.
PMID: 34775028
An accurate T-cell quantification is prognostically and therapeutically relevant in various malignancies. We previously developed a digital PCR-based approach offering a precise T-cell enumeration in small amounts of DNA. However,...