Pieter-Jan Volders
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Explore the profile of Pieter-Jan Volders including associated specialties, affiliations and a list of published articles.
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40
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1531
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Recent Articles
1.
Volders P, Aftimos P, Dedeurwaerdere F, Martens G, Canon J, Beniuga G, et al.
NPJ Precis Oncol
. 2025 Mar;
9(1):66.
PMID: 40065106
The Belgian Approach for Local Laboratory Extensive Tumor Testing (BALLETT) study assessed the feasibility of using comprehensive genomic profiling (CGP) in clinical decision-making for patients with advanced cancers. This multi-center...
2.
Froyen G, Volders P, Geerdens E, Berden S, Van der Meulen J, De Cock A, et al.
Mol Oncol
. 2025 Jan;
PMID: 39887903
Somatic multigene analysis by next-generation sequencing (NGS) is routinely integrated in medical oncology for clinical decision-making. However, with the fast-growing number of recommended and required genes as well as pan-cancer...
3.
Vromman M, Anckaert J, Bortoluzzi S, Buratin A, Chen C, Chu Q, et al.
Nat Methods
. 2025 Jan;
22(2):448.
PMID: 39825083
No abstract available.
4.
Salz R, Vorsteveld E, van der Made C, Kersten S, Stemerdink M, Riepe T, et al.
iScience
. 2024 Aug;
27(8):110471.
PMID: 39091463
We performed long-read transcriptome and proteome profiling of pathogen-stimulated peripheral blood mononuclear cells (PBMCs) from healthy donors to discover new transcript and protein isoforms expressed during immune responses to diverse...
5.
Delsupehe L, Steelandt T, Lemahieu J, Volders P, Geerdens E, Berden S, et al.
Virchows Arch
. 2023 Sep;
485(2):269-279.
PMID: 37731064
In addition to morphologic analysis, molecular diagnostic work up of Spitz tumours is often of great value for their accurate diagnosis/classification. Nowadays, next-generation sequencing (NGS) is the predominant screening method...
6.
Vromman M, Anckaert J, Bortoluzzi S, Buratin A, Chen C, Chu Q, et al.
Nat Methods
. 2023 Jul;
20(8):1159-1169.
PMID: 37443337
The detection of circular RNA molecules (circRNAs) is typically based on short-read RNA sequencing data processed using computational tools. Numerous such tools have been developed, but a systematic comparison with...
7.
Salz R, Saraiva-Agostinho N, Vorsteveld E, van der Made C, Kersten S, Stemerdink M, et al.
BMC Genomics
. 2023 Jun;
24(1):305.
PMID: 37280537
Our incomplete knowledge of the human transcriptome impairs the detection of disease-causing variants, in particular if they affect transcripts only expressed under certain conditions. These transcripts are often lacking from...
8.
Vromman M, Anckaert J, Vandesompele J, Volders P
Front Bioinform
. 2022 Oct;
2:834655.
PMID: 36304334
Circular RNA (circRNA) is a class of endogenous non-coding RNA characterized by a back-splice junction (BSJ). In general, large-scale circRNA BSJ detection is performed based on RNA sequencing data, followed...
9.
Wils G, Helsmoortel C, Volders P, Vereecke I, Milazzo M, Vandesompele J, et al.
Mol Diagn Ther
. 2022 May;
26(4):411-419.
PMID: 35633488
Introduction: Next-generation sequencing applications are becoming indispensable for clinical diagnostics. These experiments require numerous wet- and dry-laboratory steps, each one increasing the probability of a sample swap or contamination. Therefore,...
10.
Shiferaw G, Gabriels R, Bouwmeester R, Van Den Bossche T, Vandermarliere E, Martens L, et al.
J Proteome Res
. 2022 Apr;
21(5):1365-1370.
PMID: 35446579
Maintaining high sensitivity while limiting false positives is a key challenge in peptide identification from mass spectrometry data. Here, we investigate the effects of integrating the machine learning-based postprocessor Percolator...