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Phillip L R Nicolson

Explore the profile of Phillip L R Nicolson including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 299
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Recent Articles
1.
Hassan E, Sutton D, Buka R, Lowe G, Nandra T, Jacob N, et al.
Thromb Res . 2025 Jan; 247:109258. PMID: 39827813
Background: Heavy menstrual bleeding (HMB) is a significant clinical burden for premenopausal individuals treated with anticoagulation for acute venous thromboembolism (VTE). Despite its prevalence, HMB management remains poorly studied, with...
2.
Sherratt-Mayhew S, Nicolson P
EJHaem . 2024 Aug; 5(4):825-828. PMID: 39157612
Pure red cell aplasia (PRCA) is characterised by normocytic normochromic anaemia, reticulocytopenia and reduced erythroid precursors in bone marrow. PRCA as an immune-related adverse event secondary to immune checkpoint inhibitor...
3.
Smith C, Campos J, Brown H, Jooss N, Ivanova V, Harbi M, et al.
Blood Adv . 2024 Jul; 8(21):5557-5570. PMID: 38968150
Platelet C-type lectin-like receptor 2 (CLEC-2) is a hem-immunoreceptor tyrosine-based activation motif-containing receptor that has a critical role in venous thrombosis but minimal involvement in hemostasis. CLEC-2 can be blocked...
4.
Gardner J, Abrams S, Toh C, Parker A, Lovatt C, Nicolson P, et al.
NPJ Vaccines . 2024 Jun; 9(1):99. PMID: 38839821
Vaccination has proven to be a valuable tool to combat SARS-CoV-2. However, reports of rare adverse reactions such as thrombosis/thrombocytopenia syndrome after ChAdOx1 nCoV-19 vaccination have caused scientific, public and...
5.
Cooper N, Scully M, Percy C, Nicolson P, Lowe G, Bagot C, et al.
Br J Haematol . 2024 Mar; 204(6):2442-2452. PMID: 38429869
Few studies have reported the real-world use of both romiplostim and eltrombopag in immune thrombocytopenia (ITP). TRAIT was a retrospective observational study aimed to evaluate the platelet responses and adverse...
6.
Abrams S, Du M, Shaw R, Johnson C, McGuinness D, Schofield J, et al.
J Thromb Haemost . 2023 Dec; 22(4):1145-1153. PMID: 38103733
Background: Adenoviral vector-based COVID-19 vaccine-induced immune thrombotic thrombocytopenia (VITT) is rare but carries significant risks of mortality and long-term morbidity. The underlying pathophysiology of severe disease is still not fully...
7.
Buka R, Montague S, Moran L, Martin E, Slater A, Watson S, et al.
Blood . 2023 Oct; 143(1):64-69. PMID: 37883794
Platelet factor 4 (PF4) is an abundant chemokine that is released from platelet α-granules on activation. PF4 is central to the pathophysiology of vaccine-induced immune thrombocytopenia and thrombosis (VITT) in...
8.
Alenazy F, Harbi M, Kavanagh D, Price J, Brady P, Hargreaves O, et al.
J Thromb Haemost . 2023 Aug; 21(11):3236-3251. PMID: 37541591
Background: Aspirin and platelet P2Y inhibitors, such as ticagrelor, suboptimally inhibit microvascular thrombosis during ST-elevation myocardial infarction. Glycoprotein (GP) IIb/IIIa inhibitors may further inhibit this but cause excessive bleeding. Objectives:...
9.
Glancy P, Sutton D, Gomez K, Nicolson P, Buka R
EJHaem . 2023 Feb; 4(1):298-300. PMID: 36819179
No abstract available.
10.
Smith C, Harbi M, Garcia-Quintanilla L, Rookes K, Brown H, Poulter N, et al.
J Thromb Haemost . 2022 Oct; 20(12):2939-2952. PMID: 36239466
Background: New antithrombotic therapies with less effect on bleeding are needed for coronary artery disease. The Btk inhibitor ibrutinib blocks atherosclerotic plaque-mediated thrombus formation. However, it is associated with increased...