Steve P Watson
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Explore the profile of Steve P Watson including associated specialties, affiliations and a list of published articles.
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263
Citations
6626
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Recent Articles
1.
Perez-Toledo M, Beristain-Covarrubias N, Pillaye J, Persaud R, Marcial-Juarez E, Jossi S, et al.
Nat Commun
. 2025 Mar;
16(1):2356.
PMID: 40064845
Inflammation-induced thrombosis is a common consequence of bacterial infections, such as those caused by Salmonella Typhimurium (STm). The presentation of multi-organ thrombosis post-infection that develops and resolves with organ-specific kinetics...
2.
Lamerton R, Montague S, Perez-Toledo M, Watson S, Cunningham A
Platelets
. 2024 Dec;
35(1):2437241.
PMID: 39681834
Invasive non-typhoidal infections are responsible for >75 000 deaths/year and >500 000 cases/year globally. Seventy-five percent of these cases occur in Sub-Saharan Africa, an increasing number of which are from...
3.
Smith C, Campos J, Brown H, Jooss N, Ivanova V, Harbi M, et al.
Blood Adv
. 2024 Jul;
8(21):5557-5570.
PMID: 38968150
Platelet C-type lectin-like receptor 2 (CLEC-2) is a hem-immunoreceptor tyrosine-based activation motif-containing receptor that has a critical role in venous thrombosis but minimal involvement in hemostasis. CLEC-2 can be blocked...
4.
Martin E, Clark J, Montague S, Moran L, Di Y, Bull L, et al.
J Thromb Haemost
. 2024 Jun;
22(8):2378-2379.
PMID: 38902124
No abstract available.
5.
Gardner J, Abrams S, Toh C, Parker A, Lovatt C, Nicolson P, et al.
NPJ Vaccines
. 2024 Jun;
9(1):99.
PMID: 38839821
Vaccination has proven to be a valuable tool to combat SARS-CoV-2. However, reports of rare adverse reactions such as thrombosis/thrombocytopenia syndrome after ChAdOx1 nCoV-19 vaccination have caused scientific, public and...
6.
Xu R, Tiede C, Calabrese A, Cheah L, Adams T, Gauer J, et al.
Blood Adv
. 2024 Jun;
8(15):3917-3928.
PMID: 38838227
Glycoprotein VI (GPVI) plays a key role in collagen-induced platelet aggregation. Affimers are engineered binding protein alternatives to antibodies. We screened and characterized GPVI-binding Affimers as novel tools to probe...
7.
Bourne J, Perrella G, El-Awaisi J, Terry L, Tinkova V, Hogg R, et al.
J Thromb Haemost
. 2024 Apr;
22(7):2018-2026.
PMID: 38670315
Background: Free labile hemin acts as a damage-associated molecular pattern during acute and chronic hemolysis and muscle injury, supporting platelet activation and thrombosis. Objectives: To investigate the anti-thrombotic potential of...
8.
Wang X, Slater A, Lee S, Harrison N, Pollock N, Bakker S, et al.
Arch Biochem Biophys
. 2024 Feb;
754:109944.
PMID: 38395124
The collagen/fibrin(ogen) receptor, glycoprotein VI (GPVI), is a platelet activating receptor and a promising anti-thrombotic drug target. However, while agonist-induced GPVI clustering on platelet membranes has been shown to be...
9.
Buka R, Montague S, Moran L, Martin E, Slater A, Watson S, et al.
Blood
. 2023 Oct;
143(1):64-69.
PMID: 37883794
Platelet factor 4 (PF4) is an abundant chemokine that is released from platelet α-granules on activation. PF4 is central to the pathophysiology of vaccine-induced immune thrombocytopenia and thrombosis (VITT) in...
10.
Martin E, Clark J, Montague S, Moran L, Di Y, Bull L, et al.
J Thromb Haemost
. 2023 Oct;
22(1):271-285.
PMID: 37813196
Background: Clustering of the receptors glycoprotein receptor VI (GPVI), C-type lectin-like receptor 2 (CLEC-2), low-affinity immunoglobulin γ Fc region receptor II-a (FcγRIIA), and platelet endothelial aggregation receptor 1 (PEAR1) leads...