Philippe Marliere
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Explore the profile of Philippe Marliere including associated specialties, affiliations and a list of published articles.
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62
Citations
1122
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Recent Articles
11.
Pezo V, Jaziri F, Bourguignon P, Louis D, Jacobs-Sera D, Rozenski J, et al.
Science
. 2021 Apr;
372(6541):520-524.
PMID: 33926956
Bacteriophage genomes harbor the broadest chemical diversity of nucleobases across all life forms. Certain DNA viruses that infect hosts as diverse as cyanobacteria, proteobacteria, and actinobacteria exhibit wholesale substitution of...
12.
Sleiman D, Garcia P, Lagune M, Loch J, Haouz A, Taib N, et al.
Science
. 2021 Apr;
372(6541):516-520.
PMID: 33926955
Cells have two purine pathways that synthesize adenine and guanine ribonucleotides from phosphoribose via inosylate. A chemical hybrid between adenine and guanine, 2-aminoadenine (Z), replaces adenine in the DNA of...
13.
Ou Z, Ouzounis C, Wang D, Sun W, Li J, Chen W, et al.
Genome Biol Evol
. 2020 Oct;
12(12):2467-2485.
PMID: 33125064
In the context of the COVID-19 pandemic, we describe here the singular metabolic background that constrains enveloped RNA viruses to evolve toward likely attenuation in the long term, possibly after...
14.
Flamme M, Rothlisberger P, Levi-Acobas F, Chawla M, Oliva R, Cavallo L, et al.
ACS Chem Biol
. 2020 Oct;
15(11):2872-2884.
PMID: 33090769
The expansion of the genetic alphabet with additional, unnatural base pairs (UBPs) is an important and long-standing goal in synthetic biology. Nucleotides acting as ligands for the coordination of metal...
15.
Danchin A, Marliere P
Environ Microbiol
. 2020 Apr;
22(6):1977-1985.
PMID: 32291894
No abstract available.
16.
He H, Hoper R, Dodenhoft M, Marliere P, Bar-Even A
Metab Eng
. 2020 Mar;
60:1-13.
PMID: 32169542
Engineering biotechnological microorganisms to use methanol as a feedstock for bioproduction is a major goal for the synthetic metabolism community. Here, we aim to redesign the natural serine cycle for...
17.
Papastavrou N, Bande O, Marliere P, Groaz E, Herdewijn P
Chem Commun (Camb)
. 2020 Feb;
56(18):2787-2790.
PMID: 32025667
Expanding the catalytic repertoire of ribozymes to include vitamin synthesis requires efficient labelling of RNA with the substrate of interest, prior to in vitro selection. For this purpose, we rationally...
18.
Nigro G, Bourcier S, Lazennec-Schurdevin C, Schmitt E, Marliere P, Mechulam Y
J Struct Biol
. 2019 Dec;
209(2):107435.
PMID: 31862305
Polypeptides containing β-amino acids are attractive tools for the design of novel proteins having unique properties of medical or industrial interest. Incorporation of β-amino acids in vivo requires the development...
19.
Heinisch T, Schwizer F, Garabedian B, Csibra E, Jeschek M, Vallapurackal J, et al.
Chem Sci
. 2019 Aug;
10(27):6735.
PMID: 31367329
[This corrects the article DOI: 10.1039/C8SC00484F.].
20.
Luo M, Groaz E, Froeyen M, Pezo V, Jaziri F, Leonczak P, et al.
J Am Chem Soc
. 2019 Jun;
141(27):10844-10851.
PMID: 31251601
A synthetic orthogonal polymer embracing a chiral acyclic-phosphonate backbone [()-ZNA] is presented that uniquely adds to the emerging family of xenobiotic nucleic acids (XNAs). ()-ZNA consists of reiterating six-atom structural...