Philippe Letteron
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Explore the profile of Philippe Letteron including associated specialties, affiliations and a list of published articles.
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43
Citations
1499
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Recent Articles
1.
Duprilot M, Baron A, Blanquart F, Dion S, Pouget C, Letteron P, et al.
Infect Immun
. 2020 Sep;
88(12).
PMID: 32989036
O25b:H4 sequence type 131 (ST131), which is resistant to fluoroquinolones and which is a producer of CTX-M-15, is globally one of the major extraintestinal pathogenic (ExPEC) lineages. Phylogenetic analyses showed...
2.
Bustad H, Toska K, Schmitt C, Vorland M, Skjaerven L, Kallio J, et al.
Mol Ther
. 2019 Dec;
28(2):677-689.
PMID: 31810863
Mutations in hydroxymethylbilane synthase (HMBS) cause acute intermittent porphyria (AIP), an autosomal dominant disease where typically only one HMBS allele is mutated. In AIP, the accumulation of porphyrin precursors triggers...
3.
Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver
Habib A, Chokr D, Wan J, Hegde P, Mabire M, Siebert M, et al.
Gut
. 2018 Oct;
68(3):522-532.
PMID: 30301768
Objective: Sustained inflammation originating from macrophages is a driving force of fibrosis progression and resolution. Monoacylglycerol lipase (MAGL) is the rate-limiting enzyme in the degradation of monoacylglycerols. It is a...
4.
Makhezer N, Ben Khemis M, Liu D, Khichane Y, Marzaioli V, Tlili A, et al.
Mucosal Immunol
. 2018 Oct;
12(1):117-131.
PMID: 30279516
Inflammatory bowel disease (IBD) is characterized by severe and recurrent inflammation of the gastrointestinal tract, associated with altered patterns of cytokine synthesis, excessive reactive oxygen species (ROS) production, and high...
5.
Hegde P, Weiss E, Paradis V, Wan J, Mabire M, Sukriti S, et al.
Nat Commun
. 2018 Jun;
9(1):2146.
PMID: 29858567
Liver fibrosis is the common response to chronic liver injury, and leads to cirrhosis and its complications. Persistent inflammation is a driving force of liver fibrosis progression. Mucosal-associated invariant T...
6.
Rolas L, Boussif A, Weiss E, Letteron P, Haddad O, El-Benna J, et al.
Gut
. 2017 Jun;
67(8):1505-1516.
PMID: 28601846
Objective: Cirrhosis downregulates phagocyte oxidant production via their antibacterial superoxide-generating system, NADPH oxidase (NOX2) and increases patients' susceptibility to infection and mortality rate. To explore novel biochemical parameters that explain...
7.
Millot S, Delaby C, Moulouel B, Lefebvre T, Pilard N, Ducrot N, et al.
Haematologica
. 2017 Feb;
102(2):260-270.
PMID: 28143953
Hemolysis occurring in hematologic diseases is often associated with an iron loading anemia. This iron overload is the result of a massive outflow of hemoglobin into the bloodstream, but the...
8.
Hepcidin as a Major Component of Renal Antibacterial Defenses against Uropathogenic Escherichia coli
Houamel D, Ducrot N, Lefebvre T, Daher R, Moulouel B, Sari M, et al.
J Am Soc Nephrol
. 2015 Aug;
27(3):835-46.
PMID: 26293821
The iron-regulatory peptide hepcidin exhibits antimicrobial activity. Having previously shown hepcidin expression in the kidney, we addressed its role in urinary tract infection (UTI), which remains largely unknown. Experimental UTI...
9.
Guerin F, Wagner M, Line A, Zappa M, Fasseu M, Paradis V, et al.
PLoS One
. 2015 May;
10(5):e0125493.
PMID: 26020934
Background & Aims: To determine the pathogenesis of liver nodules, and lesions similar to obliterative portal venopathy, observed after portosystemic shunts or portal vein thrombosis in humans. Methods: We conducted...
10.
Arapis K, Cavin J, Gillard L, Cluzeaud F, Letteron P, Ducroc R, et al.
PLoS One
. 2015 Mar;
10(3):e0121414.
PMID: 25822172
Whereas the remodeling of intestinal mucosa after bariatric surgeries has been the matter of numerous studies to our knowledge, very few reported on the remodeling of the residual gastric mucosa....