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Philippe Barthe

Explore the profile of Philippe Barthe including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 968
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Recent Articles
1.
Lahfa M, Barthe P, de Guillen K, Cesari S, Raji M, Kroj T, et al.
PLoS Pathog . 2024 May; 20(5):e1012176. PMID: 38709846
Magnaporthe AVRs and ToxB-like (MAX) effectors constitute a family of secreted virulence proteins in the fungus Pyricularia oryzae (syn. Magnaporthe oryzae), which causes blast disease on numerous cereals and grasses....
2.
Mouhand A, Nakatani K, Kono F, Hippo Y, Matsuo T, Barthe P, et al.
Biomol NMR Assign . 2024 Mar; 18(1):65-70. PMID: 38526839
NCYM is a cis-antisense gene of MYCN oncogene and encodes an oncogenic protein that stabilizes MYCN via inhibition of GSK3b. High NCYM expression levels are associated with poor clinical outcomes...
3.
Lahfa M, Mouhand A, de Guillen K, Barthe P, Kroj T, Padilla A, et al.
Molecules . 2023 Aug; 28(16). PMID: 37630320
Does a similar 3D structure mean a similar folding pathway? This question is particularly meaningful when it concerns proteins sharing a similar 3D structure, but low sequence identity or homology....
4.
Mouhand A, Pissarra J, Delbecq S, Roumestand C, Barthe P
Biomol NMR Assign . 2023 Jul; 17(2):217-221. PMID: 37452919
Human babesiosis is a vector-borne zoonotic infection caused mostly by the Apicomplexan parasite Babesia microti, distributed worldwide. The infection can result in severe symptoms such as hemolytic anemia, especially in...
5.
Martin M, DeVisch A, Boudehen Y, Barthe P, Gutierrez C, Turapov O, et al.
Microbiol Spectr . 2023 Apr; 11(3):e0106623. PMID: 37036353
Host metabolism reprogramming is a key feature of Mycobacterium tuberculosis () infection that enables the survival of this pathogen within phagocytic cells and modulates the immune response facilitating the spread...
6.
Momin A, Mendes T, Barthe P, Faure C, Hong S, Yu P, et al.
Commun Biol . 2022 Aug; 5(1):800. PMID: 35945264
Multidomain kinases use many ways to integrate and process diverse stimuli. Here, we investigated the mechanism by which the protein tyrosine kinase 2-beta (PYK2) functions as a sensor and effector...
7.
Lahfa M, Padilla A, de Guillen K, Pissarra J, Raji M, Cesari S, et al.
Biomol NMR Assign . 2022 Jun; 16(2):305-309. PMID: 35657473
Effectors are small and very diverse proteins secreted by fungi and translocated in plant cells during infection. Among them, MAX effectors (for Magnaporthe Avrs and ToxB) were identified as a...
8.
Dubois C, Lahfa M, Pissarra J, de Guillen K, Barthe P, Kroj T, et al.
Int J Mol Sci . 2022 May; 23(10). PMID: 35628267
Despite advances in experimental and computational methods, the mechanisms by which an unstructured polypeptide chain regains its unique three-dimensional structure remains one of the main puzzling questions in biology. Single-molecule...
9.
Van Deuren V, Yang Y, de Guillen K, Dubois C, Royer C, Roumestand C, et al.
Biology (Basel) . 2021 Aug; 10(7). PMID: 34356511
Multidimensional NMR intrinsically provides multiple probes that can be used for deciphering the folding pathways of proteins: NH amide and CαHα groups are strategically located on the backbone of the...
10.
Dubois C, Planelles-Herrero V, Tillatte-Tripodi C, Delbecq S, Mammri L, Sirkia E, et al.
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33808390
When combined with NMR spectroscopy, high hydrostatic pressure is an alternative perturbation method used to destabilize globular proteins that has proven to be particularly well suited for exploring the unfolding...