Christian Roumestand
Overview
Explore the profile of Christian Roumestand including associated specialties, affiliations and a list of published articles.
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Articles
60
Citations
1184
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Recent Articles
1.
Koduru T, Hantman N, Peters E, Jaworek M, Wang J, Zhang S, et al.
Proc Natl Acad Sci U S A
. 2024 Sep;
121(39):e2413100121.
PMID: 39292747
The adenosine di-phosphate (ADP) ribosylation factor (Arf) small guanosine tri-phosphate (GTP)ases function as molecular switches to activate signaling cascades that control membrane organization in eukaryotic cells. In Arf1, the GDP/GTP...
2.
Lahfa M, Barthe P, de Guillen K, Cesari S, Raji M, Kroj T, et al.
PLoS Pathog
. 2024 May;
20(5):e1012176.
PMID: 38709846
Magnaporthe AVRs and ToxB-like (MAX) effectors constitute a family of secreted virulence proteins in the fungus Pyricularia oryzae (syn. Magnaporthe oryzae), which causes blast disease on numerous cereals and grasses....
3.
Mouhand A, Nakatani K, Kono F, Hippo Y, Matsuo T, Barthe P, et al.
Biomol NMR Assign
. 2024 Mar;
18(1):65-70.
PMID: 38526839
NCYM is a cis-antisense gene of MYCN oncogene and encodes an oncogenic protein that stabilizes MYCN via inhibition of GSK3b. High NCYM expression levels are associated with poor clinical outcomes...
4.
Lahfa M, Mouhand A, de Guillen K, Barthe P, Kroj T, Padilla A, et al.
Molecules
. 2023 Aug;
28(16).
PMID: 37630320
Does a similar 3D structure mean a similar folding pathway? This question is particularly meaningful when it concerns proteins sharing a similar 3D structure, but low sequence identity or homology....
5.
Mouhand A, Pissarra J, Delbecq S, Roumestand C, Barthe P
Biomol NMR Assign
. 2023 Jul;
17(2):217-221.
PMID: 37452919
Human babesiosis is a vector-borne zoonotic infection caused mostly by the Apicomplexan parasite Babesia microti, distributed worldwide. The infection can result in severe symptoms such as hemolytic anemia, especially in...
6.
Calio A, Dubois C, Fontanay S, Koza M, Hoh F, Roumestand C, et al.
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955607
Life is thought to have appeared in the depth of the sea under high hydrostatic pressure. Nowadays, it is known that the deep biosphere hosts a myriad of life forms...
7.
Lahfa M, Padilla A, de Guillen K, Pissarra J, Raji M, Cesari S, et al.
Biomol NMR Assign
. 2022 Jun;
16(2):305-309.
PMID: 35657473
Effectors are small and very diverse proteins secreted by fungi and translocated in plant cells during infection. Among them, MAX effectors (for Magnaporthe Avrs and ToxB) were identified as a...
8.
Dubois C, Lahfa M, Pissarra J, de Guillen K, Barthe P, Kroj T, et al.
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628267
Despite advances in experimental and computational methods, the mechanisms by which an unstructured polypeptide chain regains its unique three-dimensional structure remains one of the main puzzling questions in biology. Single-molecule...
9.
Noble R, Walther V, Roumestand C, Hochberg M, Hibner U, Lassus P
Front Ecol Evol
. 2022 Jan;
9.
PMID: 35096847
Explaining the emergence and maintenance of intratumor heterogeneity is an important question in cancer biology. Tumor cells can generate considerable subclonal diversity, which influences tumor growth rate, treatment resistance, and...
10.
Van Deuren V, Yang Y, de Guillen K, Dubois C, Royer C, Roumestand C, et al.
Biology (Basel)
. 2021 Aug;
10(7).
PMID: 34356511
Multidimensional NMR intrinsically provides multiple probes that can be used for deciphering the folding pathways of proteins: NH amide and CαHα groups are strategically located on the backbone of the...