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Philipp Rescheneder

Explore the profile of Philipp Rescheneder including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 1850
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Recent Articles
1.
Neumann T, Herzog V, Muhar M, von Haeseler A, Zuber J, Ameres S, et al.
BMC Bioinformatics . 2019 May; 20(1):258. PMID: 31109287
Background: Methods to read out naturally occurring or experimentally introduced nucleic acid modifications are emerging as powerful tools to study dynamic cellular processes. The recovery, quantification and interpretation of such...
2.
Drecktrah D, Hall L, Rescheneder P, Lybecker M, Samuels D
Front Cell Infect Microbiol . 2018 Jul; 8:231. PMID: 30027068
The Lyme disease spirochete () must tolerate nutrient stress to persist in the tick phase of its enzootic life cycle. We previously found that the stringent response mediated by Rel...
3.
Nattestad M, Goodwin S, Ng K, Baslan T, Sedlazeck F, Rescheneder P, et al.
Genome Res . 2018 Jun; 28(8):1126-1135. PMID: 29954844
The SK-BR-3 cell line is one of the most important models for HER2+ breast cancers, which affect one in five breast cancer patients. SK-BR-3 is known to be highly rearranged,...
4.
Sedlazeck F, Rescheneder P, Smolka M, Fang H, Nattestad M, von Haeseler A, et al.
Nat Methods . 2018 May; 15(6):461-468. PMID: 29713083
Structural variations are the greatest source of genetic variation, but they remain poorly understood because of technological limitations. Single-molecule long-read sequencing has the potential to dramatically advance the field, although...
5.
Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al.
Science . 2018 Apr; 360(6390):800-805. PMID: 29622725
Defining direct targets of transcription factors and regulatory pathways is key to understanding their roles in physiology and disease. We combined SLAM-seq [thiol(SH)-linked alkylation for the metabolic sequencing of RNA],...
6.
Herzog V, Reichholf B, Neumann T, Rescheneder P, Bhat P, Burkard T, et al.
Nat Methods . 2017 Sep; 14(12):1198-1204. PMID: 28945705
Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes in RNA species at steady state but obscures the intracellular dynamics of RNA transcription, processing and decay. We developed...
7.
Sedlyarova N, Rescheneder P, Magan A, Popitsch N, Rziha N, Bilusic I, et al.
Mol Cell . 2017 Jun; 67(1):30-43.e6. PMID: 28648779
In search for RNA signals that modulate transcription via direct interaction with RNA polymerase (RNAP), we deep sequenced an E. coli genomic library enriched for RNAP-binding RNAs. Many natural RNAP-binding...
8.
Popitsch N, Bilusic I, Rescheneder P, Schroeder R, Lybecker M
BMC Genomics . 2017 Jan; 18(1):28. PMID: 28056764
Background: Transmission of Borrelia burgdorferi from its tick vector to a vertebrate host requires extensive reprogramming of gene expression. Small regulatory RNAs (sRNA) have emerged in the last decade as...
9.
Gesson K, Rescheneder P, Skoruppa M, von Haeseler A, Dechat T, Foisner R
Genome Res . 2016 Jan; 26(4):462-73. PMID: 26798136
Lamins are components of the peripheral nuclear lamina and interact with heterochromatic genomic regions, termed lamina-associated domains (LADs). In contrast to lamin B1 being primarily present at the nuclear periphery,...
10.
Smolka M, Rescheneder P, Schatz M, von Haeseler A, Sedlazeck F
Genome Biol . 2015 Oct; 16:235. PMID: 26494581
Mapping reads to a genome remains challenging, especially for non-model organisms with lower quality assemblies, or for organisms with higher mutation rates. While most research has focused on speeding up...